EWSR1-NR4A3 fusion	Soft Tissue Sarcoma	EWSR1-NR4A3 fusion	Soft Tissue Sarcoma	sunitinib Sensitive: C3 – Early Trials sunitinib Sensitive : C3	sunitinib Sensitive: C3 – Early Trials sunitinib Sensitive : C3
EWSR1 mutation	Colorectal Adenocarcinoma	EWSR1 mutation	Colorectal Adenocarcinoma	sintilimab + fruquintinib Resistant: C3 – Early Trials sintilimab + fruquintinib Resistant : C3	sintilimab + fruquintinib Resistant: C3 – Early Trials sintilimab + fruquintinib Resistant : C3
EWSR1-POU5F1 fusion	Renal Cell Carcinoma	EWSR1-POU5F1 fusion	Renal Cell Carcinoma	CB-228 Sensitive: C3 – Early Trials CB-228 Sensitive : C3	CB-228 Sensitive: C3 – Early Trials CB-228 Sensitive : C3
EWSR1-FLI1 fusion	Ewing Sarcoma	EWSR1-FLI1 fusion	Ewing Sarcoma	trabectedin Sensitive: C3 – Early Trials trabectedin Sensitive : C3	trabectedin Sensitive: C3 – Early Trials trabectedin Sensitive : C3
EWSR1-CREB1 fusion	Neuroendocrine Tumor	EWSR1-CREB1 fusion	Neuroendocrine Tumor	crizotinib + pazopanib Sensitive: C4 – Case Studies crizotinib + pazopanib Sensitive : C4	crizotinib + pazopanib Sensitive: C4 – Case Studies crizotinib + pazopanib Sensitive : C4
EWSR1-FLI1 fusion	Ewing Sarcoma	EWSR1-FLI1 fusion	Ewing Sarcoma	Sensitive: C4 – Case Studies Sensitive : C4	Sensitive: C4 – Case Studies Sensitive : C4
EWSR1-TFCP2 fusion	Rhabdomyosarcoma	EWSR1-TFCP2 fusion	Rhabdomyosarcoma	crizotinib Resistant: C4 – Case Studies crizotinib Resistant : C4	crizotinib Resistant: C4 – Case Studies crizotinib Resistant : C4
EWSR1 rearrangement	Sarcoma	EWSR1 rearrangement	Sarcoma	FAC Sensitive: C4 – Case Studies FAC Sensitive : C4	FAC Sensitive: C4 – Case Studies FAC Sensitive : C4
EWSR1-CREM fusion	Sarcoma	EWSR1-CREM fusion	Sarcoma	pazopanib Sensitive: C4 – Case Studies pazopanib Sensitive : C4	pazopanib Sensitive: C4 – Case Studies pazopanib Sensitive : C4
EWSR1-FLI1 fusion	Ewing Sarcoma	EWSR1-FLI1 fusion	Ewing Sarcoma	CDK12 inhibitor Sensitive: D – Preclinical CDK12 inhibitor Sensitive : D	CDK12 inhibitor Sensitive: D – Preclinical CDK12 inhibitor Sensitive : D
EWSR1-WT1 fusion	Soft Tissue Sarcoma	EWSR1-WT1 fusion	Soft Tissue Sarcoma	trabectedin Sensitive: D – Preclinical trabectedin Sensitive : D	trabectedin Sensitive: D – Preclinical trabectedin Sensitive : D

EWSR1 (EWS RNA Binding Protein 1)

Associations(11)

Associations
(11)