H3.3K27M	Glioma	H3.3K27M	Glioma	dordaviprone Sensitive: B - Late Trials dordaviprone Sensitive : B	dordaviprone Sensitive: B - Late Trials dordaviprone Sensitive : B
NRAS mutation	Non Small Cell Lung Cancer	NRAS mutation	Non Small Cell Lung Cancer	KO-947 Sensitive: C2 – Inclusion Criteria KO-947 Sensitive : C2	KO-947 Sensitive: C2 – Inclusion Criteria KO-947 Sensitive : C2
H3.3K27M	Glioma	H3.3K27M	Glioma	bevacizumab + dordaviprone Sensitive: C3 – Early Trials bevacizumab + dordaviprone Sensitive : C3	bevacizumab + dordaviprone Sensitive: C3 – Early Trials bevacizumab + dordaviprone Sensitive : C3
BRAF mutation	Thyroid Gland Anaplastic Carcinoma	BRAF mutation	Thyroid Gland Anaplastic Carcinoma	dabrafenib + SCH772984 Sensitive: D – Preclinical dabrafenib + SCH772984 Sensitive : D	dabrafenib + SCH772984 Sensitive: D – Preclinical dabrafenib + SCH772984 Sensitive : D
EGFR overexpression	Glioblastoma	EGFR overexpression	Glioblastoma	dordaviprone Resistant: D – Preclinical dordaviprone Resistant : D	dordaviprone Resistant: D – Preclinical dordaviprone Resistant : D
AR splice variant 7	Prostate Cancer	AR splice variant 7	Prostate Cancer	darolutamide + dordaviprone Resistant: D – Preclinical darolutamide + dordaviprone Resistant : D	darolutamide + dordaviprone Resistant: D – Preclinical darolutamide + dordaviprone Resistant : D
BRAF mutation	Pancreatic Cancer	BRAF mutation	Pancreatic Cancer	SCH772984 Sensitive: D – Preclinical SCH772984 Sensitive : D	SCH772984 Sensitive: D – Preclinical SCH772984 Sensitive : D
KRAS mutation	Melanoma	KRAS mutation	Melanoma	SCH772984 Sensitive: D – Preclinical SCH772984 Sensitive : D	SCH772984 Sensitive: D – Preclinical SCH772984 Sensitive : D
KRAS mutation	Pancreatic Cancer	KRAS mutation	Pancreatic Cancer	SCH772984 Sensitive: D – Preclinical SCH772984 Sensitive : D	SCH772984 Sensitive: D – Preclinical SCH772984 Sensitive : D
BRAF mutation	Melanoma	BRAF mutation	Melanoma	SCH772984 Sensitive: D – Preclinical SCH772984 Sensitive : D	SCH772984 Sensitive: D – Preclinical SCH772984 Sensitive : D
BRAF V600E	Colorectal Cancer	BRAF V600E	Colorectal Cancer	DEL-22379 Sensitive: D – Preclinical DEL-22379 Sensitive : D	DEL-22379 Sensitive: D – Preclinical DEL-22379 Sensitive : D
BRAF V600E	Thyroid Gland Carcinoma	BRAF V600E	Thyroid Gland Carcinoma	dasatinib + SCH772984 Sensitive: D – Preclinical dasatinib + SCH772984 Sensitive : D	dasatinib + SCH772984 Sensitive: D – Preclinical dasatinib + SCH772984 Sensitive : D

ERK inhibitor

ERK inhibitor

Associations(23)

Associations
(23)