Contact us to learn more about

our Premium Content: News alerts, weekly reports and conference planners

DRUG CLASS:

Electron transport complex I inhibitor

DRUG CLASS:

Electron transport complex I inhibitor

Contact us to learn more about our Premium Content:

News alerts, weekly reports and conference planners

Related drugs:

‹

IACS-010759 (9)

iobenguane I 131 (0)

IACS-010759 (9)

iobenguane I 131 (0)

›

MYC rearrangement + BCL2 rearrangement	Diffuse Large B Cell Lymphoma	MYC rearrangement + BCL2 rearrangement	Diffuse Large B Cell Lymphoma	IACS-010759 Sensitive: D – Preclinical IACS-010759 Sensitive : D	IACS-010759 Sensitive: D – Preclinical IACS-010759 Sensitive : D
NPM1 mutation	Acute Myelogenous Leukemia	NPM1 mutation	Acute Myelogenous Leukemia	venetoclax + IACS-010759 Sensitive: D – Preclinical venetoclax + IACS-010759 Sensitive : D	venetoclax + IACS-010759 Sensitive: D – Preclinical venetoclax + IACS-010759 Sensitive : D
FLT3-ITD mutation	Acute Myelogenous Leukemia	FLT3-ITD mutation	Acute Myelogenous Leukemia	venetoclax + IACS-010759 Sensitive: D – Preclinical venetoclax + IACS-010759 Sensitive : D	venetoclax + IACS-010759 Sensitive: D – Preclinical venetoclax + IACS-010759 Sensitive : D
IDH1 mutation	Acute Myelogenous Leukemia	IDH1 mutation	Acute Myelogenous Leukemia	venetoclax + IACS-010759 Sensitive: D – Preclinical venetoclax + IACS-010759 Sensitive : D	venetoclax + IACS-010759 Sensitive: D – Preclinical venetoclax + IACS-010759 Sensitive : D
NRAS mutation	Acute Myelogenous Leukemia	NRAS mutation	Acute Myelogenous Leukemia	venetoclax + IACS-010759 Sensitive: D – Preclinical venetoclax + IACS-010759 Sensitive : D	venetoclax + IACS-010759 Sensitive: D – Preclinical venetoclax + IACS-010759 Sensitive : D
FLT3 mutation	Acute Myelogenous Leukemia	FLT3 mutation	Acute Myelogenous Leukemia	quizartinib + IACS-010759 Sensitive: D – Preclinical quizartinib + IACS-010759 Sensitive : D	quizartinib + IACS-010759 Sensitive: D – Preclinical quizartinib + IACS-010759 Sensitive : D
CEBPA mutation	Acute Myelogenous Leukemia	CEBPA mutation	Acute Myelogenous Leukemia	venetoclax + IACS-010759 Sensitive: D – Preclinical venetoclax + IACS-010759 Sensitive : D	venetoclax + IACS-010759 Sensitive: D – Preclinical venetoclax + IACS-010759 Sensitive : D
BCL2 overexpression	Acute Myelogenous Leukemia	BCL2 overexpression	Acute Myelogenous Leukemia	IACS-010759 Resistant: D – Preclinical IACS-010759 Resistant : D	IACS-010759 Resistant: D – Preclinical IACS-010759 Resistant : D
NOTCH1 mutation	T Acute Lymphoblastic Leukemia	NOTCH1 mutation	T Acute Lymphoblastic Leukemia	IACS-010759 Sensitive: D – Preclinical IACS-010759 Sensitive : D	IACS-010759 Sensitive: D – Preclinical IACS-010759 Sensitive : D