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DRUG:
IACS-010759
i
Other names:
IACS-010759, IACS-10759
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News alerts, weekly reports and conference planners
Associations
(9)
News
Trials
Company:
UT MD Anderson Cancer Center
Drug class:
Electron transport complex I inhibitor
Related drugs:
‹
iobenguane I 131 (0)
atovaquone (0)
iobenguane I 131 (0)
atovaquone (0)
›
Associations
(9)
News
Trials
VERI cancer hierarchy
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MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
IACS-010759
Sensitive: D – Preclinical
IACS-010759
Sensitive
:
D
IACS-010759
Sensitive: D – Preclinical
IACS-010759
Sensitive
:
D
NPM1 mutation
Acute Myelogenous Leukemia
NPM1 mutation
Acute Myelogenous Leukemia
venetoclax + IACS-010759
Sensitive: D – Preclinical
venetoclax + IACS-010759
Sensitive
:
D
venetoclax + IACS-010759
Sensitive: D – Preclinical
venetoclax + IACS-010759
Sensitive
:
D
FLT3-ITD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation
Acute Myelogenous Leukemia
venetoclax + IACS-010759
Sensitive: D – Preclinical
venetoclax + IACS-010759
Sensitive
:
D
venetoclax + IACS-010759
Sensitive: D – Preclinical
venetoclax + IACS-010759
Sensitive
:
D
IDH1 mutation
Acute Myelogenous Leukemia
IDH1 mutation
Acute Myelogenous Leukemia
venetoclax + IACS-010759
Sensitive: D – Preclinical
venetoclax + IACS-010759
Sensitive
:
D
venetoclax + IACS-010759
Sensitive: D – Preclinical
venetoclax + IACS-010759
Sensitive
:
D
NRAS mutation
Acute Myelogenous Leukemia
NRAS mutation
Acute Myelogenous Leukemia
venetoclax + IACS-010759
Sensitive: D – Preclinical
venetoclax + IACS-010759
Sensitive
:
D
venetoclax + IACS-010759
Sensitive: D – Preclinical
venetoclax + IACS-010759
Sensitive
:
D
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
quizartinib + IACS-010759
Sensitive: D – Preclinical
quizartinib + IACS-010759
Sensitive
:
D
quizartinib + IACS-010759
Sensitive: D – Preclinical
quizartinib + IACS-010759
Sensitive
:
D
CEBPA mutation
Acute Myelogenous Leukemia
CEBPA mutation
Acute Myelogenous Leukemia
venetoclax + IACS-010759
Sensitive: D – Preclinical
venetoclax + IACS-010759
Sensitive
:
D
venetoclax + IACS-010759
Sensitive: D – Preclinical
venetoclax + IACS-010759
Sensitive
:
D
BCL2 overexpression
Acute Myelogenous Leukemia
BCL2 overexpression
Acute Myelogenous Leukemia
IACS-010759
Resistant: D – Preclinical
IACS-010759
Resistant
:
D
IACS-010759
Resistant: D – Preclinical
IACS-010759
Resistant
:
D
NOTCH1 mutation
T Acute Lymphoblastic Leukemia
NOTCH1 mutation
T Acute Lymphoblastic Leukemia
IACS-010759
Sensitive: D – Preclinical
IACS-010759
Sensitive
:
D
IACS-010759
Sensitive: D – Preclinical
IACS-010759
Sensitive
:
D
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