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BIOMARKER:

EGFR mutation + CDKN2A mutation

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Entrez ID:

Related biomarkers:

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EGFR exon 19 deletion (79)

EGFR amplification (52)

CDKN2A deletion (20)

EGFR exon 18 deletion (3)

EGFR exon 2-7 deletion + EGFR amplification (2)

IKZF1 deletion + CDKN2A deletion (2)

EGFR amplification + ERBB2 amplification (1)

EGFR exon 19 deletion + HER-2 amplification (1)

EGFR exon 21 deletion (1)

CDKN2A deletion + MTAP deletion (1)

MTAP deletion + CDKN2A deletion + CDKN2B deletion + BAP1 deletion (1)

EGFR T790M + exon 19 deletion (0)

EGFR amplifcation (0)

IKZF1 deletion + CDKN2A deletion + CDKN2B deletion + PAX5 deletion (0)

EGFR exon 19 deletion (79)

EGFR amplification (52)

CDKN2A deletion (20)

EGFR exon 18 deletion (3)

EGFR exon 2-7 deletion + EGFR amplification (2)

IKZF1 deletion + CDKN2A deletion (2)

EGFR amplification + ERBB2 amplification (1)

EGFR exon 19 deletion + HER-2 amplification (1)

EGFR exon 21 deletion (1)

CDKN2A deletion + MTAP deletion (1)

MTAP deletion + CDKN2A deletion + CDKN2B deletion + BAP1 deletion (1)

EGFR T790M + exon 19 deletion (0)

EGFR amplifcation (0)

IKZF1 deletion + CDKN2A deletion + CDKN2B deletion + PAX5 deletion (0)

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EGFR mutation + CDKN2A mutation	Non Small Cell Lung Cancer	EGFR mutation + CDKN2A mutation	Non Small Cell Lung Cancer	osimertinib Resistant: C3 – Early Trials osimertinib Resistant : C3	osimertinib Resistant: C3 – Early Trials osimertinib Resistant : C3
EGFR mutation + CDKN2A mutation	Non Small Cell Lung Cancer	EGFR mutation + CDKN2A mutation	Non Small Cell Lung Cancer	Tyrosine kinase inhibitor Sensitive: C3 – Early Trials Tyrosine kinase inhibitor Sensitive : C3	Tyrosine kinase inhibitor Sensitive: C3 – Early Trials Tyrosine kinase inhibitor Sensitive : C3