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CANCER:

Cutaneous T-cell Lymphoma

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No biomarker	Cutaneous T-cell Lymphoma	No biomarker	Cutaneous T-cell Lymphoma	KT-333 Sensitive: B - Late Trials GlobeNewswire - 1 week (New B) KT-333 Sensitive : B GlobeNewswire - 1wk	KT-333 Sensitive: B - Late Trials GlobeNewswire - 1 week KT-333 Sensitive : B GlobeNewswire - 1 week - (New B)
TNFRSF8 positive	Cutaneous T-cell Lymphoma	TNFRSF8 positive	Cutaneous T-cell Lymphoma	brentuximab vedotin Sensitive: A1 - Approval SOHO 2023 - 3 weeks (New C4) brentuximab vedotin Sensitive : A1 SOHO 2023 - 3wk	brentuximab vedotin Sensitive: A1 - Approval SOHO 2023 - 3 weeks brentuximab vedotin Sensitive : A1 SOHO 2023 - 3 weeks - (New C4)
No biomarker	Cutaneous T-cell Lymphoma	No biomarker	Cutaneous T-cell Lymphoma	bexarotene oral Sensitive: A1 - Approval bexarotene oral Sensitive : A1	bexarotene oral Sensitive: A1 - Approval bexarotene oral Sensitive : A1
No biomarker	Cutaneous T-cell Lymphoma	No biomarker	Cutaneous T-cell Lymphoma	vorinostat Sensitive: A1 - Approval vorinostat Sensitive : A1	vorinostat Sensitive: A1 - Approval vorinostat Sensitive : A1
IL2RA expression	Cutaneous T-cell Lymphoma	IL2RA expression	Cutaneous T-cell Lymphoma	denileukin diftitox Sensitive: A1 - Approval denileukin diftitox Sensitive : A1	denileukin diftitox Sensitive: A1 - Approval denileukin diftitox Sensitive : A1
No biomarker	Cutaneous T-cell Lymphoma	No biomarker	Cutaneous T-cell Lymphoma	denileukin diftitox Sensitive: A1 - Approval denileukin diftitox Sensitive : A1	denileukin diftitox Sensitive: A1 - Approval denileukin diftitox Sensitive : A1
No biomarker	Cutaneous T-cell Lymphoma	No biomarker	Cutaneous T-cell Lymphoma	RP6530 Sensitive: B - Late Trials RP6530 Sensitive : B	RP6530 Sensitive: B - Late Trials RP6530 Sensitive : B
TNFRSF8 expression	Cutaneous T-cell Lymphoma	TNFRSF8 expression	Cutaneous T-cell Lymphoma	brentuximab vedotin Sensitive: B - Late Trials brentuximab vedotin Sensitive : B	brentuximab vedotin Sensitive: B - Late Trials brentuximab vedotin Sensitive : B
PD-L1 underexpression	Cutaneous T-cell Lymphoma	PD-L1 underexpression	Cutaneous T-cell Lymphoma	durvalumab + lenalidomide Sensitive: C3 – Early Trials durvalumab + lenalidomide Sensitive : C3	durvalumab + lenalidomide Sensitive: C3 – Early Trials durvalumab + lenalidomide Sensitive : C3
RPS6 underexpression	Cutaneous T-cell Lymphoma	RPS6 underexpression	Cutaneous T-cell Lymphoma	ruxolitinib Sensitive: C3 – Early Trials ruxolitinib Sensitive : C3	ruxolitinib Sensitive: C3 – Early Trials ruxolitinib Sensitive : C3
ICOS underexpression	Cutaneous T-cell Lymphoma	ICOS underexpression	Cutaneous T-cell Lymphoma	durvalumab Sensitive: C3 – Early Trials durvalumab Sensitive : C3	durvalumab Sensitive: C3 – Early Trials durvalumab Sensitive : C3
PD-1 overexpression	Cutaneous T-cell Lymphoma	PD-1 overexpression	Cutaneous T-cell Lymphoma	pembrolizumab Sensitive: C3 – Early Trials pembrolizumab Sensitive : C3	pembrolizumab Sensitive: C3 – Early Trials pembrolizumab Sensitive : C3
CD70 expression	Cutaneous T-cell Lymphoma	CD70 expression	Cutaneous T-cell Lymphoma	ARGX-110 Sensitive: C3 – Early Trials ARGX-110 Sensitive : C3	ARGX-110 Sensitive: C3 – Early Trials ARGX-110 Sensitive : C3
IL10-L	Cutaneous T-cell Lymphoma	IL10-L	Cutaneous T-cell Lymphoma	pembrolizumab Sensitive: C3 – Early Trials pembrolizumab Sensitive : C3	pembrolizumab Sensitive: C3 – Early Trials pembrolizumab Sensitive : C3
TNFA-L	Cutaneous T-cell Lymphoma	TNFA-L	Cutaneous T-cell Lymphoma	pembrolizumab Sensitive: C3 – Early Trials pembrolizumab Sensitive : C3	pembrolizumab Sensitive: C3 – Early Trials pembrolizumab Sensitive : C3
CCL20-L	Cutaneous T-cell Lymphoma	CCL20-L	Cutaneous T-cell Lymphoma	pembrolizumab Sensitive: C3 – Early Trials pembrolizumab Sensitive : C3	pembrolizumab Sensitive: C3 – Early Trials pembrolizumab Sensitive : C3
TNFRSF8 expression	Cutaneous T-cell Lymphoma	TNFRSF8 expression	Cutaneous T-cell Lymphoma	TUB-010 Sensitive: D – Preclinical TUB-010 Sensitive : D	TUB-010 Sensitive: D – Preclinical TUB-010 Sensitive : D