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BIOMARKER:
CHEK2 mutation + ATM mutation + BRCA2 mutation
i
Other names:
BRCA2, BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, Breast cancer 2, early onset, CHEK2, bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53, Checkpoint kinase 2, ATM, ATA, ATC, ATD, ATDC, TEL1, TELO1, ATM serine/threonine kinase
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Entrez ID:
675
;
472
;
11200
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
BRCA2 mutation (200)
ATM mutation (51)
BRCA wild-type (19)
CHEK2 mutation (10)
BRCA1 mutation + BRCA2 mutation (4)
BRCA2 A902fs*2 (3)
BRCA2 mutation + CHEK2 mutation (2)
BRCA2 mutation + TP53 mutation (2)
BRCA2 rearrangement (2)
ATM mutation + IGH mutation (2)
ATM S978fs*12 (2)
EGFR mutation + ATM mutation (2)
APC mutation + BRCA2 mutation (1)
BRCA2 1153insT (1)
BRCA2 5396insC (1)
BRCA2 I2315T (1)
BRCA2 L557* (1)
BRCA2 N255fs + D252fs (1)
BRCA2 Y1655* + TP53 mutation (1)
BRCA2 biallelic inactivation (1)
BRCA2 mutation + ATM mutation (1)
BRCA2 mutation + CDK12 mutation (1)
BRCA2 mutation + SPOP mutation (1)
BRCA2 mutation + TP53 D816Y (1)
EGFR exon 19 deletion + BRCA2 mutation (1)
ASXL1 mutation + ATM mutation (1)
ATM D2721N (1)
ATM G2695D (1)
ATM PI2629fs* (1)
ATM S1905Ifs*25 + STK11 K262Sfs*25 (1)
ATM W2845 (1)
ATM biallelic inactivation (1)
ATM biallelic mutation (1)
ATM mutation + CDK12 mutation (1)
ATM L804fs*4 (1)
BRCA1 mutation + ATM mutation (1)
EGFR exon 19 deletion + ATM S1455fs*36 + MYC E62K (1)
KRAS G12C + ATM wild-type (1)
KRAS mutation + ATM mutation (1)
RET M918T + ATM L804fs*4 + ATM S978fs*12 (1)
TP53 mutation + ATM mutation (1)
BRCA2 E260fs (0)
BRCA2 N255_R259delinsIK (0)
BRCA2 N255fs (0)
BRCA2 N255fs + BRCA2 N255_R259delinsIK + BRCA2 E260fs (0)
ATM R337H (0)
ATM T2333fs* (0)
BRCA2 mutation (200)
ATM mutation (51)
BRCA wild-type (19)
CHEK2 mutation (10)
BRCA1 mutation + BRCA2 mutation (4)
BRCA2 A902fs*2 (3)
BRCA2 mutation + CHEK2 mutation (2)
BRCA2 mutation + TP53 mutation (2)
BRCA2 rearrangement (2)
ATM mutation + IGH mutation (2)
ATM S978fs*12 (2)
EGFR mutation + ATM mutation (2)
APC mutation + BRCA2 mutation (1)
BRCA2 1153insT (1)
BRCA2 5396insC (1)
BRCA2 I2315T (1)
BRCA2 L557* (1)
BRCA2 N255fs + D252fs (1)
BRCA2 Y1655* + TP53 mutation (1)
BRCA2 biallelic inactivation (1)
BRCA2 mutation + ATM mutation (1)
BRCA2 mutation + CDK12 mutation (1)
BRCA2 mutation + SPOP mutation (1)
BRCA2 mutation + TP53 D816Y (1)
EGFR exon 19 deletion + BRCA2 mutation (1)
ASXL1 mutation + ATM mutation (1)
ATM D2721N (1)
ATM G2695D (1)
ATM PI2629fs* (1)
ATM S1905Ifs*25 + STK11 K262Sfs*25 (1)
ATM W2845 (1)
ATM biallelic inactivation (1)
ATM biallelic mutation (1)
ATM mutation + CDK12 mutation (1)
ATM L804fs*4 (1)
BRCA1 mutation + ATM mutation (1)
EGFR exon 19 deletion + ATM S1455fs*36 + MYC E62K (1)
KRAS G12C + ATM wild-type (1)
KRAS mutation + ATM mutation (1)
RET M918T + ATM L804fs*4 + ATM S978fs*12 (1)
TP53 mutation + ATM mutation (1)
BRCA2 E260fs (0)
BRCA2 N255_R259delinsIK (0)
BRCA2 N255fs (0)
BRCA2 N255fs + BRCA2 N255_R259delinsIK + BRCA2 E260fs (0)
ATM R337H (0)
ATM T2333fs* (0)
›
Associations
News
Trials
VERI cancer hierarchy
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CHEK2 mutation + ATM mutation + BRCA2 mutation
Non Small Cell Lung Cancer
CHEK2 mutation + ATM mutation + BRCA2 mutation
Non Small Cell Lung Cancer
cetuximab + avelumab
Sensitive: C3 – Early Trials
cetuximab + avelumab
Sensitive
:
C3
cetuximab + avelumab
Sensitive: C3 – Early Trials
cetuximab + avelumab
Sensitive
:
C3
^
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