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BIOMARKER:

CHEK2 mutation + ATM mutation + BRCA2 mutation

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Entrez ID:

675; 472; 11200

Related biomarkers:

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HRD + BRCA2 mutation (7)

ATM deletion + SF3B1 mutation (4)

BRCA2 mutation + HR positive (3)

HR positive + BRCA2 mutation (3)

BRCA2 mutation + HER-2 negative (2)

HR negative + BRCA2 mutation (2)

Chr del(11q) + ATM mutation (2)

ALK rearrangement + BRCA2 F2801fs (1)

BRCA1 mutation + BRCA2 mutation + TMB-H (1)

BRCA2 deletion + ATM mutation (1)

BRCA2 mutation + AKR1C3 overexpression (1)

BRCA2 mutation + ER positive (1)

BRCA2 mutation + ER positive + PGR positive (1)

BRCA2 mutation + RB1 deletion (1)

BRCA2 mutation + TMB-H (1)

BRCA2 mutation + TMB-L (1)

HR positive + BRCA2 mutation + PALB2 mutation (1)

ATM expression + ATM T2333fs* + EGFR negative (1)

ER positive + BRCA2 mutation (0)

HRD + BRCA2 mutation (7)

ATM deletion + SF3B1 mutation (4)

BRCA2 mutation + HR positive (3)

HR positive + BRCA2 mutation (3)

BRCA2 mutation + HER-2 negative (2)

HR negative + BRCA2 mutation (2)

Chr del(11q) + ATM mutation (2)

ALK rearrangement + BRCA2 F2801fs (1)

BRCA1 mutation + BRCA2 mutation + TMB-H (1)

BRCA2 deletion + ATM mutation (1)

BRCA2 mutation + AKR1C3 overexpression (1)

BRCA2 mutation + ER positive (1)

BRCA2 mutation + ER positive + PGR positive (1)

BRCA2 mutation + RB1 deletion (1)

BRCA2 mutation + TMB-H (1)

BRCA2 mutation + TMB-L (1)

HR positive + BRCA2 mutation + PALB2 mutation (1)

ATM expression + ATM T2333fs* + EGFR negative (1)

ER positive + BRCA2 mutation (0)

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CHEK2 mutation + ATM mutation + BRCA2 mutation

Non Small Cell Lung Cancer

cetuximab + avelumab

Sensitive: C3 – Early Trials

cetuximab + avelumab

cetuximab + avelumab

Sensitive: C3 – Early Trials

cetuximab + avelumab