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GENE:

CAV1 (Caveolin 1)

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Entrez ID:

FAT1 mutation + FAT1 underexpression + CAV1 overexpression	Squamous Cell Carcinoma of Head and Neck	FAT1 mutation + FAT1 underexpression + CAV1 overexpression	Squamous Cell Carcinoma of Head and Neck	Immunotherapy Resistant: C3 – Early Trials Immunotherapy Resistant : C3	Immunotherapy Resistant: C3 – Early Trials Immunotherapy Resistant : C3
FAT1 mutation + FAT1 underexpression + CAV1 overexpression	Squamous Cell Carcinoma of Head and Neck	FAT1 mutation + FAT1 underexpression + CAV1 overexpression	Squamous Cell Carcinoma of Head and Neck	EGFR inhibitor Resistant: C3 – Early Trials EGFR inhibitor Resistant : C3	EGFR inhibitor Resistant: C3 – Early Trials EGFR inhibitor Resistant : C3
HER-2 positive + CAV1 overexpression	Gastric Cancer	HER-2 positive + CAV1 overexpression	Gastric Cancer	trastuzumab Resistant: C3 – Early Trials trastuzumab Resistant : C3	trastuzumab Resistant: C3 – Early Trials trastuzumab Resistant : C3
CAV1 overexpression	Pancreatic Ductal Adenocarcinoma	CAV1 overexpression	Pancreatic Ductal Adenocarcinoma	gemcitabine + albumin-bound paclitaxel Resistant: C3 – Early Trials gemcitabine + albumin-bound paclitaxel Resistant : C3	gemcitabine + albumin-bound paclitaxel Resistant: C3 – Early Trials gemcitabine + albumin-bound paclitaxel Resistant : C3
CAV1 overexpression + CAV2 overexpression	HER2 Negative Breast Cancer	CAV1 overexpression + CAV2 overexpression	HER2 Negative Breast Cancer	albumin-bound paclitaxel Sensitive: C3 – Early Trials albumin-bound paclitaxel Sensitive : C3	albumin-bound paclitaxel Sensitive: C3 – Early Trials albumin-bound paclitaxel Sensitive : C3
CAV1 expression	Non Small Cell Lung Cancer	CAV1 expression	Non Small Cell Lung Cancer	amlodipine/atorvastatin Sensitive: D – Preclinical amlodipine / atorvastatin Sensitive : D	amlodipine/atorvastatin Sensitive: D – Preclinical amlodipine / atorvastatin Sensitive : D
CAV1 overexpression	Lung Cancer	CAV1 overexpression	Lung Cancer	SSH20 Sensitive: D – Preclinical SSH20 Sensitive : D	SSH20 Sensitive: D – Preclinical SSH20 Sensitive : D
CAV1 overexpression	Pancreatic Cancer	CAV1 overexpression	Pancreatic Cancer	SSH20 Sensitive: D – Preclinical SSH20 Sensitive : D	SSH20 Sensitive: D – Preclinical SSH20 Sensitive : D