^
Association details:
| Biomarker: | CAV1 expression |
|---|---|
| Cancer: | Non Small Cell Lung Cancer |
| Drug: | amlodipine/atorvastatin (HMG-CoA reductase inhibitor, Ca2+ channel antagonist) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
CAV1 - GLUT3 signaling is important for cellular energy and can be targeted by Atorvastatin in Non-Small Cell Lung Cancer
Excerpt:
Atorvastatin suppresses growth by inhibiting Cav1 expression in tumors in cell culture system and in in vivo models.
Secondary therapy:
paclitaxel + carboplatin
DOI:
10.7150/thno.35805
