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BIOMARKER:

BRCA wild-type

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Entrez ID:

Related biomarkers:

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BRCA1 fusion (0)

BRCA2 fusion (0)

BRCA1 fusion (0)

BRCA2 fusion (0)

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BRCA wild-type	Ovarian Cancer	BRCA wild-type	Ovarian Cancer	rucaparib Sensitive: A2 - Guideline rucaparib Sensitive : A2	rucaparib Sensitive: A2 - Guideline rucaparib Sensitive : A2
BRCA wild-type	Ovarian Cancer	BRCA wild-type	Ovarian Cancer	ABT-888 Sensitive: B - Late Trials ABT-888 Sensitive : B	ABT-888 Sensitive: B - Late Trials ABT-888 Sensitive : B
BRCA wild-type	Ovarian Cancer	BRCA wild-type	Ovarian Cancer	bevacizumab + olaparib + durvalumab Sensitive: B - Late Trials bevacizumab + olaparib + durvalumab Sensitive : B	bevacizumab + olaparib + durvalumab Sensitive: B - Late Trials bevacizumab + olaparib + durvalumab Sensitive : B
BRCA wild-type	Ovarian Cancer	BRCA wild-type	Ovarian Cancer	AZD1775 Sensitive: C2 – Inclusion Criteria AZD1775 Sensitive : C2	AZD1775 Sensitive: C2 – Inclusion Criteria AZD1775 Sensitive : C2
BRCA wild-type	Triple Negative Breast Cancer	BRCA wild-type	Triple Negative Breast Cancer	olaparib + alpelisib Sensitive: C3 – Early Trials olaparib + alpelisib Sensitive : C3	olaparib + alpelisib Sensitive: C3 – Early Trials olaparib + alpelisib Sensitive : C3
BRCA wild-type	Breast Cancer	BRCA wild-type	Breast Cancer	talazoparib Sensitive: C3 – Early Trials talazoparib Sensitive : C3	talazoparib Sensitive: C3 – Early Trials talazoparib Sensitive : C3
BRCA wild-type	Triple Negative Breast Cancer	BRCA wild-type	Triple Negative Breast Cancer	ACR-368 Sensitive: C3 – Early Trials ACR-368 Sensitive : C3	ACR-368 Sensitive: C3 – Early Trials ACR-368 Sensitive : C3
BRCA wild-type	Ovarian Cancer	BRCA wild-type	Ovarian Cancer	pembrolizumab + bevacizumab + olaparib Sensitive: C3 – Early Trials pembrolizumab + bevacizumab + olaparib Sensitive : C3	pembrolizumab + bevacizumab + olaparib Sensitive: C3 – Early Trials pembrolizumab + bevacizumab + olaparib Sensitive : C3
BRCA wild-type	Triple Negative Breast Cancer	BRCA wild-type	Triple Negative Breast Cancer	talazoparib + ZEN-3694 Sensitive: C3 – Early Trials talazoparib + ZEN-3694 Sensitive : C3	talazoparib + ZEN-3694 Sensitive: C3 – Early Trials talazoparib + ZEN-3694 Sensitive : C3
BRCA wild-type	Ovarian Cancer	BRCA wild-type	Ovarian Cancer	bortezomib Sensitive: C3 – Early Trials bortezomib Sensitive : C3	bortezomib Sensitive: C3 – Early Trials bortezomib Sensitive : C3
BRCA wild-type	Ovarian Cancer	BRCA wild-type	Ovarian Cancer	carboplatin + paclitaxel Sensitive: C3 – Early Trials carboplatin + paclitaxel Sensitive : C3	carboplatin + paclitaxel Sensitive: C3 – Early Trials carboplatin + paclitaxel Sensitive : C3
BRCA wild-type	Ovarian Cancer	BRCA wild-type	Ovarian Cancer	bevacizumab + olaparib + atezolizumab Sensitive: C3 – Early Trials bevacizumab + olaparib + atezolizumab Sensitive : C3	bevacizumab + olaparib + atezolizumab Sensitive: C3 – Early Trials bevacizumab + olaparib + atezolizumab Sensitive : C3
BRCA wild-type	Triple Negative Breast Cancer	BRCA wild-type	Triple Negative Breast Cancer	carboplatin + paclitaxel + cyclophosphamide Sensitive: C3 – Early Trials carboplatin + paclitaxel + cyclophosphamide Sensitive : C3	carboplatin + paclitaxel + cyclophosphamide Sensitive: C3 – Early Trials carboplatin + paclitaxel + cyclophosphamide Sensitive : C3
BRCA wild-type	HER2 Negative Breast Cancer	BRCA wild-type	HER2 Negative Breast Cancer	DAN-222 Sensitive: C3 – Early Trials DAN-222 Sensitive : C3	DAN-222 Sensitive: C3 – Early Trials DAN-222 Sensitive : C3
BRCA wild-type	HER2 Negative Breast Cancer	BRCA wild-type	HER2 Negative Breast Cancer	niraparib + DAN-222 Sensitive: C3 – Early Trials niraparib + DAN-222 Sensitive : C3	niraparib + DAN-222 Sensitive: C3 – Early Trials niraparib + DAN-222 Sensitive : C3
BRCA wild-type	Triple Negative Breast Cancer	BRCA wild-type	Triple Negative Breast Cancer	MLN4924 Sensitive: D – Preclinical MLN4924 Sensitive : D	MLN4924 Sensitive: D – Preclinical MLN4924 Sensitive : D
BRCA wild-type	Ovarian Cancer	BRCA wild-type	Ovarian Cancer	olaparib + ART12 Sensitive: D – Preclinical olaparib + ART12 Sensitive : D	olaparib + ART12 Sensitive: D – Preclinical olaparib + ART12 Sensitive : D
BRCA wild-type	Ovarian Cancer	BRCA wild-type	Ovarian Cancer	olaparib + cediranib + 3-AP Sensitive: D – Preclinical olaparib + cediranib + 3-AP Sensitive : D	olaparib + cediranib + 3-AP Sensitive: D – Preclinical olaparib + cediranib + 3-AP Sensitive : D
BRCA wild-type	Triple Negative Breast Cancer	BRCA wild-type	Triple Negative Breast Cancer	olaparib + AZD1775 Sensitive: D – Preclinical olaparib + AZD1775 Sensitive : D	olaparib + AZD1775 Sensitive: D – Preclinical olaparib + AZD1775 Sensitive : D