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BIOMARKER:
BRAF V600E + PIK3CA mutation
i
Other names:
BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1, PIK3CA, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha, Phosphoinositide-3-kinase, catalytic, alpha polypeptide,
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Entrez ID:
673
;
5290
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
PIK3CA amplification (12)
BRAF L485-P490 deletion (6)
BRAF amplification (1)
PIK3CA amplification (12)
BRAF L485-P490 deletion (6)
BRAF amplification (1)
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VERI cancer hierarchy
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BRAF V600E + PIK3CA mutation
Colorectal Cancer
BRAF V600E + PIK3CA mutation
Colorectal Cancer
cetuximab + alpelisib + encorafenib
Resistant: C3 – Early Trials
cetuximab + alpelisib + encorafenib
Resistant
:
C3
cetuximab + alpelisib + encorafenib
Resistant: C3 – Early Trials
cetuximab + alpelisib + encorafenib
Resistant
:
C3
BRAF V600E + PIK3CA mutation
Colorectal Cancer
BRAF V600E + PIK3CA mutation
Colorectal Cancer
cetuximab + binimetinib + encorafenib
Resistant: C3 – Early Trials
cetuximab + binimetinib + encorafenib
Resistant
:
C3
cetuximab + binimetinib + encorafenib
Resistant: C3 – Early Trials
cetuximab + binimetinib + encorafenib
Resistant
:
C3
BRAF V600E + PIK3CA mutation
Colorectal Cancer
BRAF V600E + PIK3CA mutation
Colorectal Cancer
cetuximab + encorafenib
Resistant: C3 – Early Trials
cetuximab + encorafenib
Resistant
:
C3
cetuximab + encorafenib
Resistant: C3 – Early Trials
cetuximab + encorafenib
Resistant
:
C3
BRAF V600E + PIK3CA mutation
Astrocytoma
BRAF V600E + PIK3CA mutation
Astrocytoma
vemurafenib + everolimus
Sensitive: C4 – Case Studies
vemurafenib + everolimus
Sensitive
:
C4
vemurafenib + everolimus
Sensitive: C4 – Case Studies
vemurafenib + everolimus
Sensitive
:
C4
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