^
Association details:
Evidence:
Evidence Level:
Sensitive: D – Preclinical
New
Source:
Title:

CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations

Excerpt:
Interestingly, the D594G mutated melanoma line WM3629 was highly sensitive to growth inhibition following treatment with sorafenib, whereas the cell lines with the V600E, G469E and K601E BRAF mutations were growth inhibited, but not as highly sensitive.
DOI:
10.1038/onc.2008.362