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BIOMARKER:

BCL2 underexpression

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Entrez ID:

Related biomarkers:

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BCL2/BCL2L1 ratio elevation (3)

BCL2 rearrangement + MYC amplification (2)

BCL2/MCL1 ratio elevation (2)

BCL2 elevation + IGH elevation (1)

BCL2 fusion + EZH2 mutation (1)

Chr t(11;14) + BCL2 : BCL2L1 ratio elevation (1)

Chr t(11;14) + BCL2 overexpression (1)

MYC amplification + BCL2 amplification + TNFRSF8 expression (1)

PTEN deletion + BCL2 translocation (1)

BCL2/BAX ratio elevation (0)

BCL2/BCL2L1 ratio elevation (3)

BCL2 rearrangement + MYC amplification (2)

BCL2/MCL1 ratio elevation (2)

BCL2 elevation + IGH elevation (1)

BCL2 fusion + EZH2 mutation (1)

Chr t(11;14) + BCL2 : BCL2L1 ratio elevation (1)

Chr t(11;14) + BCL2 overexpression (1)

MYC amplification + BCL2 amplification + TNFRSF8 expression (1)

PTEN deletion + BCL2 translocation (1)

BCL2/BAX ratio elevation (0)

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BCL2 underexpression	Multiple Myeloma	BCL2 underexpression	Multiple Myeloma	venetoclax Resistant: D – Preclinical venetoclax Resistant : D	venetoclax Resistant: D – Preclinical venetoclax Resistant : D
BCL2 underexpression	Ewing Sarcoma	BCL2 underexpression	Ewing Sarcoma	venetoclax Sensitive: D – Preclinical venetoclax Sensitive : D	venetoclax Sensitive: D – Preclinical venetoclax Sensitive : D