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BIOMARKER:
BCL2 G101V + SF3B1 mutation
i
Other names:
BCL2, Bcl-2, PPP1R50, B-cell CLL/lymphoma 2, SF3B1, Splicing Factor 3b Subunit 1, Splicing Factor 3b Subunit 1 155kDa, Spliceosome-Associated Protein 155, Splicing Factor 3B Subunit 1, SF3b155, SAP155, Pre-MRNA Splicing Factor SF3b 155 KDa Subunit, Pre-MRNA-Splicing Factor SF3b 155 KDa Subunit, Splicing Factor 3b Subunit 1 155kD, Pre-MRNA Processing 10, SAP 155, Hsh155, PRPF10, PRP10, MDS
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Entrez ID:
596
;
23451
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
ATM deletion + SF3B1 mutation (4)
BCL2/BCL2L1 ratio elevation (3)
Chr del(13q) + Chr del(11q) + SF3B1 mutation (3)
BCL2 rearrangement + MYC amplification (2)
BCL2/MCL1 ratio elevation (2)
BCL2 elevation + IGH elevation (1)
BCL2 fusion + EZH2 mutation (1)
Chr t(11;14) + BCL2 : BCL2L1 ratio elevation (1)
Chr t(11;14) + BCL2 overexpression (1)
MYC amplification + BCL2 amplification + TNFRSF8 expression (1)
PTEN deletion + BCL2 translocation (1)
SF3B1 mutation + Chr del(5q) (1)
BCL2/BAX ratio elevation (0)
ATM deletion + SF3B1 mutation (4)
BCL2/BCL2L1 ratio elevation (3)
Chr del(13q) + Chr del(11q) + SF3B1 mutation (3)
BCL2 rearrangement + MYC amplification (2)
BCL2/MCL1 ratio elevation (2)
BCL2 elevation + IGH elevation (1)
BCL2 fusion + EZH2 mutation (1)
Chr t(11;14) + BCL2 : BCL2L1 ratio elevation (1)
Chr t(11;14) + BCL2 overexpression (1)
MYC amplification + BCL2 amplification + TNFRSF8 expression (1)
PTEN deletion + BCL2 translocation (1)
SF3B1 mutation + Chr del(5q) (1)
BCL2/BAX ratio elevation (0)
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BCL2 G101V + SF3B1 mutation
Chronic Lymphocytic Leukemia
BCL2 G101V + SF3B1 mutation
Chronic Lymphocytic Leukemia
venetoclax
Resistant: C3 – Early Trials
venetoclax
Resistant
:
C3
venetoclax
Resistant: C3 – Early Trials
venetoclax
Resistant
:
C3
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