PTEN deletion	Prostate Cancer	PTEN deletion	Prostate Cancer	ATM kinase inhibitor Sensitive: D – Preclinical ATM kinase inhibitor Sensitive : D	ATM kinase inhibitor Sensitive: D – Preclinical ATM kinase inhibitor Sensitive : D
TP53 mutation	Triple Negative Breast Cancer	TP53 mutation	Triple Negative Breast Cancer	AZD1390 Sensitive: D – Preclinical AZD1390 Sensitive : D	AZD1390 Sensitive: D – Preclinical AZD1390 Sensitive : D
TP53 mutation	HER2 Positive Breast Cancer	TP53 mutation	HER2 Positive Breast Cancer	AZD1390 Sensitive: D – Preclinical AZD1390 Sensitive : D	AZD1390 Sensitive: D – Preclinical AZD1390 Sensitive : D
TP53 mutation	Glioblastoma	TP53 mutation	Glioblastoma	AZD1390 Sensitive: D – Preclinical AZD1390 Sensitive : D	AZD1390 Sensitive: D – Preclinical AZD1390 Sensitive : D
ATM W2845	Melanoma	ATM W2845	Melanoma	talazoparib + KU-55933 Sensitive: D – Preclinical talazoparib + KU-55933 Sensitive : D	talazoparib + KU-55933 Sensitive: D – Preclinical talazoparib + KU-55933 Sensitive : D
DDR	Triple Negative Breast Cancer	DDR	Triple Negative Breast Cancer	AZD1390 Sensitive: D – Preclinical AZD1390 Sensitive : D	AZD1390 Sensitive: D – Preclinical AZD1390 Sensitive : D
HER-2 positive	HER2 Positive Breast Cancer	HER-2 positive	HER2 Positive Breast Cancer	AZD1390 Sensitive: D – Preclinical AZD1390 Sensitive : D	AZD1390 Sensitive: D – Preclinical AZD1390 Sensitive : D
ATM overexpression	Endometrial Cancer	ATM overexpression	Endometrial Cancer	olaparib + KU-55933 Sensitive: D – Preclinical olaparib + KU-55933 Sensitive : D	olaparib + KU-55933 Sensitive: D – Preclinical olaparib + KU-55933 Sensitive : D

ATM kinase inhibitor

ATM kinase inhibitor

Associations(8)

Associations
(8)