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BIOMARKER:

ALK F1174L

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Other names: NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor
Entrez ID:
ALK F1174L
NSCLC
X-396
Sensitive: C3 – Early Trials
ALK F1174L
NSCLC
ceritinib
Resistant: C3 – Early Trials
ALK F1174L
Neuroblastoma
crizotinib
Resistant: D – Preclinical
ALK F1174L
Neuroblastoma
AZD3463
Sensitive: D – Preclinical
ALK F1174L
Neuroblastoma
alectinib
Sensitive: D – Preclinical
ALK F1174L
Neuroblastoma
TAE-684
Sensitive: D – Preclinical