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BIOMARKER:

ABCG2 overexpression

i
Other names: ABCG2, ABCP, BCRP, CD338, EST157481, MXR, ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
Entrez ID:
ABCG2 overexpression
Osteosarcoma
MAP
Resistant: C3 – Early Trials
ABCG2 overexpression
Head and Neck Cancer
paclitaxel
Resistant: C3 – Early Trials
ABCG2 overexpression
Breast Cancer
paclitaxel
Resistant: D – Preclinical
ABCG2 overexpression
CRC
oxaliplatin
Resistant: D – Preclinical
ABCG2 overexpression
CRC
PF-05212384
Resistant: D – Preclinical
ABCG2 overexpression
Solid Tumor
TP-3654 + IT-141
Sensitive: D – Preclinical
ABCG2 overexpression
Solid Tumor
mitoxantrone + TP-3654
Sensitive: D – Preclinical
ABCG2 overexpression
Solid Tumor
topotecan + TP-3654
Sensitive: D – Preclinical