^
Association details:
| Biomarker: | ABCG2 overexpression |
|---|---|
| Cancer: | Colorectal Cancer |
| Drug: | oxaliplatin (DNA synthesis inhibitor, DNA cross linking agent) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Oxaliplatin resistance in colorectal cancer cells is mediated via activation of ABCG2 to alleviate ER stress induced apoptosis
Excerpt:
...mRNA and protein expression of ABCG2 and phosphorylation of NF-κB was significantly higher in OXA-R than parental cells.
DOI:
10.1002/jcp.26406
