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    Association details:
    Biomarker:ABCG2 overexpression
    Cancer:Colorectal Cancer
    Drug:oxaliplatin (DNA synthesis inhibitor, DNA cross linking agent)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: D – Preclinical
    New
    Source:
    J Cell Physiol
    Title:

    Oxaliplatin resistance in colorectal cancer cells is mediated via activation of ABCG2 to alleviate ER stress induced apoptosis

    Excerpt:
    ...mRNA and protein expression of ABCG2 and phosphorylation of NF-κB was significantly higher in OXA-R than parental cells.
    DOI:
    10.1002/jcp.26406