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    Association details:
    Biomarker:ABCG2 overexpression
    Cancer:Breast Cancer
    Drug:paclitaxel (Tubulin inhibitor)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: D – Preclinical
    Source:
    Toxicol Appl Pharmacol
    Title:

    Characterization of acquired paclitaxel resistance of breast cancer cells and involvement of ABC transporters

    Published date:
    11/01/2016
    Excerpt:
    We found up-regulation of ABCG2/BCRP and ABCC4 proteins only in paclitaxel-resistant SK-BR-3 cells.
    DOI:
    10.1016/j.taap.2016.09.020