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BIOMARKER:
ABCB1 overexpression
i
Other names:
ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1, ATP-binding cassette, sub-family B (MDR/TAP), member 1
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Entrez ID:
5243
Related biomarkers:
Expression
Mutation
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Associations
News
Trials
VERI cancer hierarchy
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ABCB1 overexpression
Squamous Cell Carcinoma of Head and Neck
ABCB1 overexpression
Squamous Cell Carcinoma of Head and Neck
cisplatin + 5-fluorouracil
Sensitive: C3 – Early Trials
cisplatin + 5-fluorouracil
Sensitive
:
C3
cisplatin + 5-fluorouracil
Sensitive: C3 – Early Trials
cisplatin + 5-fluorouracil
Sensitive
:
C3
ABCB1 overexpression
Head and Neck Cancer
ABCB1 overexpression
Head and Neck Cancer
paclitaxel
Resistant: C3 – Early Trials
paclitaxel
Resistant
:
C3
paclitaxel
Resistant: C3 – Early Trials
paclitaxel
Resistant
:
C3
ABCB1 overexpression
Non Small Cell Lung Cancer
ABCB1 overexpression
Non Small Cell Lung Cancer
paclitaxel
Resistant: D – Preclinical
paclitaxel
Resistant
:
D
paclitaxel
Resistant: D – Preclinical
paclitaxel
Resistant
:
D
ABCB1 overexpression
Multiple Myeloma
ABCB1 overexpression
Multiple Myeloma
carfilzomib
Resistant: D – Preclinical
carfilzomib
Resistant
:
D
carfilzomib
Resistant: D – Preclinical
carfilzomib
Resistant
:
D
ABCB1 overexpression
Colorectal Cancer
ABCB1 overexpression
Colorectal Cancer
PF-05212384
Resistant: D – Preclinical
PF-05212384
Resistant
:
D
PF-05212384
Resistant: D – Preclinical
PF-05212384
Resistant
:
D
ABCB1 overexpression
Ovarian Cancer
ABCB1 overexpression
Ovarian Cancer
lapatinib + poziotinib
Sensitive: D – Preclinical
lapatinib + poziotinib
Sensitive
:
D
lapatinib + poziotinib
Sensitive: D – Preclinical
lapatinib + poziotinib
Sensitive
:
D
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