^
    BIOMARKER:

    ABCB1 overexpression

    i
    Other names: ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1, ATP-binding cassette, sub-family B (MDR/TAP), member 1
    Entrez ID:
    5243
    Related biomarkers:
    Expression
    Mutation
    ABCB1 overexpression
    SCCHN
    cisplatin + 5-fluorouracil
    Sensitive: C3 – Early Trials
    ABCB1 overexpression
    Head and Neck Cancer
    paclitaxel
    Resistant: C3 – Early Trials
    ABCB1 overexpression
    NSCLC
    paclitaxel
    Resistant: D – Preclinical
    ABCB1 overexpression
    Multiple Myeloma
    carfilzomib
    Resistant: D – Preclinical
    ABCB1 overexpression
    CRC
    PF-05212384
    Resistant: D – Preclinical
    ABCB1 overexpression
    Ovarian Cancer
    lapatinib + HM 78136B
    Sensitive: D – Preclinical