Login
Evidence Feed
About
Diagnostics
New
Top genes
FAQ
Contact us
^
Login
Contact us
to learn more about
our Premium Content: News alerts, weekly reports and conference planners
BIOMARKER:
FLT3-TKD mutation
i
Other names:
FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
Contact us
to learn more about our Premium Content:
News alerts, weekly reports and conference planners
Entrez ID:
2322
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
FLT3 overexpression (3)
FLT3 expression (2)
FLT3-ITD expression (2)
FLT3 overexpression (3)
FLT3 expression (2)
FLT3-ITD expression (2)
›
Related tests:
LeukoStrat® CDx FLT3 Mutation Assay (6)
LeukoStrat® CDx FLT3 Mutation Assay (6)
Associations
(13)
News
Trials
Search handles
@AaronGoodman33
@hemedoc
Search handles
@AaronGoodman33
@hemedoc
Filter by
Latest
1year
NPM1 or CBF in FLT3-TKD-mutated AML identifies a favourable subtype where midostaurin improves only EFS and not OS. Here is an interesting analysis from RATIFY. https://t.co/RKRqB0ucfs (@RanjitKSMD)
1 year ago
FLT3 (Fms-related tyrosine kinase 3) • NPM1 (Nucleophosmin 1)
|
FLT3-TKD mutation
|
Rydapt (midostaurin)
over2years
Great question. Issue of prognostic significance of FLT3-TKD mutations in AML often comes up. Cant resist posting the (old) paper from my PhD studing UK AML trial data. If anything TKD associated with a more favourable prognosis (quite distinct to ITD): https://t.co/UvMLWA91qn (@AdamMead_Oxford)
over 2 years ago
FLT3 (Fms-related tyrosine kinase 3)
|
FLT3-TKD mutation
over2years
AML Question!!! 40 year old with inv(16) AML treated with 7+3->CR. HiDAC x 3. Unfortunately 2 years later presents with relapsed disease. NGS with FLT3 TKD mutation (VAF 30%). Cytogenetics inv(16). Patient is fit. WBC 50,000, ANC 100, Plt 15. You recommend (off trial) (@AaronGoodman33)
over 2 years ago
Clinical • Next-generation sequencing
|
FLT3 (Fms-related tyrosine kinase 3)
|
FLT3-TKD mutation
over3years
#ASH20 #leusm Perl: Important to remember Sorafenib and Quizartinib are not effective for FLT3-TKD mutations. (@hemedoc)
over 3 years ago
FLT3 (Fms-related tyrosine kinase 3)
|
FLT3-TKD mutation
|
sorafenib • Vanflyta (quizartinib)
Share
^
^
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login