Portrait HER2 assay enables quantitative assessment of both HER2 protein expression (via IF) and HER2/neu gene amplification (via FISH) to identify patients who could benefit from anti-HER2 ADC treatment. Because of market expansion into HER2-low patients, ANGLE has developed a quantitative HER2 assay to enable accurate stratification of patient populations throughout the treatment pathway given HER2 status can change over time.
Cancer:
Breast Cancer
Gene:
HER-2 (Human epidermal growth factor receptor 2)
HER-2 (Human epidermal growth factor receptor 2)
Drug:
BB-1701
Method:
Fluorescence in situ hybridization (FISH) / Immunofluorescence (IF)