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Portrait Flex assay

ANGLE developed the immunofluorescence (IF) Portrait Flex assay for the detection of epithelial and mesenchymal circulating tumour cells (CTCs) as well as those undergoing the epithelial-mesenchymal transition (EMTing). Additionally, the assay offers the customer the possibility of adding any bespoke protein biomarker, depending on its needs. The assay has high sensitivity and specificity (>90%) for epithelial and mesenchymal CTCs, which are known to be involved in cancer metastasis and drug resistance and was launched in late 2022 as an offering to pharma services customers.