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The Brightplex T cell exhaustion (TCE) panel includes 5 biomarkers (CD3, CD8, PD1, TIM3 and LAG3) to assess the expression of three immune checkpoints on T cells. This panel is intended to be used in clinical research to identify patients susceptible to respond to new immunotherapies especially in the context of the resistance to anti PD(L)1 treatment.
Cancer:
Non Small Cell Lung Cancer
Gene:
CD8 (cluster of differentiation 8), LAG3 (Lymphocyte Activating 3)
Method:
Immunohistochemistry (IHC)