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our Premium Content: News alerts, weekly reports and conference plannersTEST:ColoSeq™
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Company:
University of WashingtonType:
Laboratory Developed Test
Related tests:
ColoSeq™ is a comprehensive genetic test for hereditary colon cancer that uses next-generation sequencing to detect most mutations in AKT1, APC, AXIN2, BMPR1A, CDH1, CHEK2, CTNNA1, EPCAM, GALNT12, GREM1, MLH1, MSH2, MSH3, MSH6, MUTYH, NTHL1, PDGFRA, PIK3CA, PMS2, POLD1, POLE, PTEN, RPS20, SMAD4, STK11, and TP53. The assay completely sequences all exons, introns, and flanking regions of these genes AND detects large deletions and duplications.
Cancer:
Colon Cancer, Endometrial Cancer
Gene:
AKT1 (V-akt murine thymoma viral oncogene homolog 1), APC (APC Regulator Of WNT Signaling Pathway), CDH1 (Cadherin 1), CHEK2 (Checkpoint kinase 2), CTNNA1 (Catenin Alpha 1), EPCAM (Epithelial cell adhesion molecule)
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AKT1 (V-akt murine thymoma viral oncogene homolog 1), APC (APC Regulator Of WNT Signaling Pathway), CDH1 (Cadherin 1), CHEK2 (Checkpoint kinase 2), CTNNA1 (Catenin Alpha 1), EPCAM (Epithelial cell adhesion molecule), MLH1 (MutL homolog 1), MSH2 (MutS Homolog 2), MSH3 (MutS Homolog 3), MSH6 (MutS homolog 6), MUTYH (MutY homolog), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), PMS2 (PMS1 protein homolog 2), POLD1 (DNA Polymerase Delta 1), POLE (DNA Polymerase Epsilon), PTEN (Phosphatase and tensin homolog), SMAD4 (SMAD family member 4), STK11 (Serine/threonine kinase 11), TP53 (Tumor protein P53)
Method:
Next-Generation Sequencing (NGS)
