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TEST:
CNV+ Breast Cancer NGS Panel

Company:
NuProbe
Type:
Laboratory Developed Test
Related tests:

Details

Evidence
News
The CNV+ Breast Cancer NGS Panel covers 84 frequently mutated cancer hotspots in 14 genes and CNVs of HER2, amplified in 10-20% of breast cancers and guide treatment with trastuzumab (HERCEPTIN). It utilizes unique molecular identifiers(UMI) and PCR to accurately quantify SNVs and Indels down to 0.2% VAF as well as detect CNVs in HER2 above 2.04 copies and below 1.97 copies from cfDNA.
Cancer:
Breast Cancer
Gene:
AKT1 (V-akt murine thymoma viral oncogene homolog 1), AKT3 (V-akt murine thymoma viral oncogene homolog 3), AR (Androgen receptor), BRAF (B-raf proto-oncogene), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset)
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Drug:
Herceptin (trastuzumab)
Method:
Next-Generation Sequencing (NGS)