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BIOMARKER:

KIT D820A

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Entrez ID:

Related biomarkers:

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KIT mutation (32)

KIT exon 11 mutation (13)

KIT exon 9 mutation (9)

KIT exon 13 mutation (6)

KIT exon 17 mutation (6)

KIT wild-type (3)

KIT W557_V559delinsF (2)

KIT exon 11 mutation + KIT exon 17 mutation (2)

KIT exon 18 mutation (2)

KIT exon 8 mutation (2)

BRAF G466V + KIT K509Q (1)

KDR Q472H + KIT M541L (1)

KIT M552_V555delMYEV (1)

KIT V559A + KIT N822I (1)

KIT V559_E561del (1)

KIT W557_V559>C (1)

KIT W557_V559>F (1)

KIT exon 11 W557_K558delins (1)

KIT exon 14 mutation (1)

KIT exon 17 mutation + KIT exon 18 mutation (1)

KIT translocation (1)

NR4A3 rearrangement + KIT mutation (1)

KIT rs3733542 (0)

KIT mutation (32)

KIT exon 11 mutation (13)

KIT exon 9 mutation (9)

KIT exon 13 mutation (6)

KIT exon 17 mutation (6)

KIT wild-type (3)

KIT W557_V559delinsF (2)

KIT exon 11 mutation + KIT exon 17 mutation (2)

KIT exon 18 mutation (2)

KIT exon 8 mutation (2)

BRAF G466V + KIT K509Q (1)

KDR Q472H + KIT M541L (1)

KIT M552_V555delMYEV (1)

KIT V559A + KIT N822I (1)

KIT V559_E561del (1)

KIT W557_V559>C (1)

KIT W557_V559>F (1)

KIT exon 11 W557_K558delins (1)

KIT exon 14 mutation (1)

KIT exon 17 mutation + KIT exon 18 mutation (1)

KIT translocation (1)

NR4A3 rearrangement + KIT mutation (1)

KIT rs3733542 (0)

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over1year

Activity of Anlotinib in the Second-Line Therapy of Metastatic Gastrointestinal Stromal Tumors: A Prospective, Multicenter, In Vitro Study. (PubMed, Oncologist)

Anlotinib showed moderate antitumor activity in drug-resistant GIST cell lines in vitro, and good PFS and better tolerance in second-line therapy study.

over 1 year ago

Preclinical • Clinical Trial,Phase II • Journal • Stroma • Metastases

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KIT (KIT proto-oncogene, receptor tyrosine kinase)

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KIT mutation • KIT N822K • KIT exon 13 mutation • KIT V654A • KIT D820A

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imatinib • Focus V (anlotinib) • sunitinib