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BIOMARKER:
KIT exon 11 mutation
i
Other names:
KIT, C-Kit, CD117, PBT, SCFR, Stem Cell Factor Receptor, V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
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Entrez ID:
3815
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
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KIT exon 11 mutation
Gastric Cancer
KIT exon 11 mutation
Gastric Cancer
imatinib
Sensitive: B - Late Trials
imatinib
Sensitive
:
B
imatinib
Sensitive: B - Late Trials
imatinib
Sensitive
:
B
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
ripretinib
Sensitive: B - Late Trials
ripretinib
Sensitive
:
B
ripretinib
Sensitive: B - Late Trials
ripretinib
Sensitive
:
B
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
regorafenib
Sensitive: B - Late Trials
regorafenib
Sensitive
:
B
regorafenib
Sensitive: B - Late Trials
regorafenib
Sensitive
:
B
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
avapritinib
Resistant: C2 – Inclusion Criteria
avapritinib
Resistant
:
C2
avapritinib
Resistant: C2 – Inclusion Criteria
avapritinib
Resistant
:
C2
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
imatinib
Sensitive: C2 – Inclusion Criteria
imatinib
Sensitive
:
C2
imatinib
Sensitive: C2 – Inclusion Criteria
imatinib
Sensitive
:
C2
KIT exon 11 mutation
Melanoma
KIT exon 11 mutation
Melanoma
nilotinib
Sensitive: C2 – Inclusion Criteria
nilotinib
Sensitive
:
C2
nilotinib
Sensitive: C2 – Inclusion Criteria
nilotinib
Sensitive
:
C2
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
ponatinib
Sensitive: C2 – Inclusion Criteria
ponatinib
Sensitive
:
C2
ponatinib
Sensitive: C2 – Inclusion Criteria
ponatinib
Sensitive
:
C2
KIT exon 11 mutation
Melanoma
KIT exon 11 mutation
Melanoma
imatinib
Sensitive: C3 – Early Trials
imatinib
Sensitive
:
C3
imatinib
Sensitive: C3 – Early Trials
imatinib
Sensitive
:
C3
KIT exon 11 mutation
Melanoma
KIT exon 11 mutation
Melanoma
sunitinib
Sensitive: C3 – Early Trials
sunitinib
Sensitive
:
C3
sunitinib
Sensitive: C3 – Early Trials
sunitinib
Sensitive
:
C3
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
nilotinib
Sensitive: C3 – Early Trials
nilotinib
Sensitive
:
C3
nilotinib
Sensitive: C3 – Early Trials
nilotinib
Sensitive
:
C3
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
sunitinib
Sensitive: C3 – Early Trials
sunitinib
Sensitive
:
C3
sunitinib
Sensitive: C3 – Early Trials
sunitinib
Sensitive
:
C3
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
anlotinib
Sensitive: C3 – Early Trials
anlotinib
Sensitive
:
C3
anlotinib
Sensitive: C3 – Early Trials
anlotinib
Sensitive
:
C3
KIT exon 11 mutation
Melanoma
KIT exon 11 mutation
Melanoma
dasatinib
Resistant: C4 – Case Studies
dasatinib
Resistant
:
C4
dasatinib
Resistant: C4 – Case Studies
dasatinib
Resistant
:
C4
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