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BIOMARKER:

KIT exon 11 mutation

i
Other names: KIT, C-Kit, CD117, PBT, SCFR, Stem Cell Factor Receptor, V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Entrez ID:
KIT exon 11 mutation
Melanoma
sunitinib
Sensitive: A2 - Guideline
KIT exon 11 mutation
Melanoma
nilotinib
Sensitive: A2 - Guideline
KIT exon 11 mutation
Gastric Cancer
imatinib
Sensitive: B - Late Trials
KIT exon 11 mutation
GIST
ripretinib
Sensitive: B - Late Trials
KIT exon 11 mutation
GIST
imatinib
Sensitive: C2 – Inclusion Criteria
KIT exon 11 mutation
GIST
ponatinib
Sensitive: C2 – Inclusion Criteria
KIT exon 11 mutation
Melanoma
imatinib
Sensitive: C3 – Early Trials
KIT exon 11 mutation
GIST
nilotinib
Sensitive: C3 – Early Trials
KIT exon 11 mutation
GIST
sunitinib
Sensitive: C3 – Early Trials
KIT exon 11 mutation
GIST
avapritinib
Resistant: C4 – Case Studies
KIT exon 11 mutation
Melanoma
dasatinib
Resistant: C4 – Case Studies