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BIOMARKER:

KIT mutation

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Other names: KIT, C-Kit, CD117, PBT, SCFR, Stem Cell Factor Receptor, V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
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Entrez ID:
KIT mutation
Melanoma
imatinib + toripalimab
Sensitive
:
C3
ESMO 2022 - 3 weeks - (New C3)
KIT mutation
Non Small Cell Lung Cancer
Immunotherapy
Resistant
:
C3
ESMO 2022 - 3 weeks - (New C3)
KIT mutation
Thymic Carcinoma
sunitinib
Sensitive
:
A2
KIT mutation
Cutaneous Melanoma
imatinib
Sensitive
:
A2
KIT mutation
Gastrointestinal Stromal Tumor
ripretinib
Sensitive
:
B
KIT mutation
Gastrointestinal Stromal Tumor
pimitespib
Sensitive
:
B
KIT mutation
Gastrointestinal Stromal Tumor
avapritinib
Sensitive
:
C2
KIT mutation
Gastrointestinal Stromal Tumor
imatinib
Sensitive
:
C2
KIT mutation
Melanoma
imatinib
Sensitive
:
C2
KIT mutation
Melanoma
sunitinib
Sensitive
:
C2
KIT mutation
Melanoma
nivolumab
Sensitive
:
C2
KIT mutation
Gastrointestinal Stromal Tumor
sunitinib + PLX9486
Sensitive
:
C3
KIT mutation
Acute Myelogenous Leukemia
LY3009120
Sensitive
:
C3
KIT mutation
Mucosal Melanoma
PD1 inhibitor
Sensitive
:
C3
KIT mutation
Acute Myelogenous Leukemia
ivosidenib
Resistant
:
C3
KIT mutation
Mucosal Melanoma
temozolomide
Sensitive
:
C3
KIT mutation
Mucosal Melanoma
cisplatin + dacarbazine
Sensitive
:
C3
KIT mutation
Cutaneous Melanoma
PD1 inhibitor
Sensitive
:
C3
KIT mutation
Melanoma
ripretinib
Sensitive
:
C3
KIT mutation
Melanoma
temozolomide + rivoceranib
Sensitive
:
C3
KIT mutation
Gastrointestinal Stromal Tumor
AZD1775 + avapritinib
Sensitive
:
D
KIT mutation
Acute Myelogenous Leukemia
cabozantinib tablet
Sensitive
:
D