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DRUG:

GST-HG16

i
Other names: GST-HG16, GST HG 161
Company:
Fujian Cosunter, WuXi AppTec
Drug class:
c-MET inhibitor
Related drugs:
4years
[VIRTUAL] First-in-human (FIH) phase I study of GST-HG161, a potent and highly selective c-met inhibitor, in patients with advanced solid tumor. (ASCO 2020)
GST-HG161 has been well tolerated to date in study patients with a manageable safety profile. The dose escalation is expected to continue to the proposed 7th cohort at 900 mg. Research Funding: Cosunter Co., Ltd,
Clinical • P1 data
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MET (MET proto-oncogene, receptor tyrosine kinase)
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MET exon 14 mutation • MET expression
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GST-HG16