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    DRUG:

    flonoltinib

    Associations

    News

    Trials
    Company:
    Baoling Bio
    Drug class:
    JAK2 inhibitor, FLT3 inhibitor
    Related drugs:
    Associations

    News

    Trials
    4ms
    Study on tissue distribution, metabolite profiling, and excretion of [C]-labeled flonoltinib maleate in rats. (PubMed, J Pharm Biomed Anal)
    A minor fraction of FM (<10 %) was excreted through renal excretion in the form of urine. Integration of the current results with previous pharmacokinetic investigations of FM in rats and dogs enables a comprehensive elucidation of the in vivo ADME processes and characteristics of FM, thereby establishing a solid foundation for subsequent clinical investigations of FM.
    Preclinical • Journal
    |
    FLT3 (Fms-related tyrosine kinase 3) • JAK2 (Janus kinase 2)
    |
    flonoltinib
    over1year
    Study of Flonoltinib Maleate Tablets in the Treatment of Severe Novel Coronavirus (COVID-19) Infection (clinicaltrials.gov)
    P=N/A, N=66, Recruiting, Chengdu Zenitar Biomedical Technology Co., Ltd
    New trial
    |
    IL6 (Interleukin 6)
    |
    flonoltinib