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DRUG:

flonoltinib

Associations
Company:
Baoling Bio
Drug class:
JAK2 inhibitor, FLT3 inhibitor
Related drugs:
Associations
5ms
Flunotinib Maleate Phase II Intermediate-High Risk Bone Fiber Clinical Trial (clinicaltrials.gov)
P2, N=75, Recruiting, Chengdu Zenitar Biomedical Technology Co., Ltd
New P2 trial
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Jakafi (ruxolitinib) • flonoltinib
10ms
Study on tissue distribution, metabolite profiling, and excretion of [C]-labeled flonoltinib maleate in rats. (PubMed, J Pharm Biomed Anal)
A minor fraction of FM (<10 %) was excreted through renal excretion in the form of urine. Integration of the current results with previous pharmacokinetic investigations of FM in rats and dogs enables a comprehensive elucidation of the in vivo ADME processes and characteristics of FM, thereby establishing a solid foundation for subsequent clinical investigations of FM.
Preclinical • Journal
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FLT3 (Fms-related tyrosine kinase 3) • JAK2 (Janus kinase 2)
|
flonoltinib
almost2years
New trial
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IL6 (Interleukin 6)
|
flonoltinib