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DRUG:

BRL-301

i
Other names: BRL-301, CD19-UCART, BRL301, BRL 301
Associations
Company:
BRL Medicine
Drug class:
CD19-targeted CAR-T immunotherapy
Related drugs:
Associations
1m
Universal CAR-T Cells (BRL-301) in Relapse or Refractory Autoimmune Diseases (clinicaltrials.gov)
P=N/A, N=15, Enrolling by invitation, Bioray Laboratories | Recruiting --> Enrolling by invitation
Enrollment status • CAR T-Cell Therapy
|
CD19 (CD19 Molecule)
|
CD19 expression
|
BRL-301
12ms
Universal CAR-T Cells (BRL-301) in Refractory Systemic Lupus Erythematosus (clinicaltrials.gov)
P=N/A, N=12, Recruiting, Bioray Laboratories | Not yet recruiting --> Recruiting
Enrollment open • CAR T-Cell Therapy
|
CD19 expression
|
BRL-301
over1year
U-CART: Safety and Efficacy Evaluation of CD19-UCART (clinicaltrials.gov)
P=N/A, N=20, Suspended, Bioray Laboratories | Trial primary completion date: Jun 2023 --> Dec 2023
Trial primary completion date
|
CD19 (CD19 Molecule)
|
CD19 positive • CD19 expression
|
cyclophosphamide • BRL-301
almost2years
Safety and Efficacy Evaluation of Next-generation CD19-UCART (clinicaltrials.gov)
P1, N=20, Not yet recruiting, Bioray Laboratories | Initiation date: Dec 2022 --> Dec 2023
Trial initiation date • CAR T-Cell Therapy
|
CD19 (CD19 Molecule)
|
CD19 positive
|
cyclophosphamide • BRL-301
almost2years
U-CART: Safety and Efficacy Evaluation of CD19-UCART (clinicaltrials.gov)
P=N/A, N=20, Suspended, Bioray Laboratories | Trial completion date: Dec 2022 --> Dec 2023 | Trial primary completion date: Dec 2022 --> Jun 2023
Trial completion date • Trial primary completion date
|
CD19 (CD19 Molecule)
|
CD19 positive • CD19 expression
|
cyclophosphamide • BRL-301
2years
Safety and Efficacy Evaluation of Next-generation CD19-UCART (clinicaltrials.gov)
P1, N=20, Not yet recruiting, Bioray Laboratories | Initiation date: Jun 2022 --> Dec 2022
Trial initiation date • CAR T-Cell Therapy
|
CD19 (CD19 Molecule)
|
CD19 positive
|
cyclophosphamide • BRL-301
2years
U-CART: Safety and Efficacy Evaluation of CD19-UCART (clinicaltrials.gov)
P=N/A, N=20, Suspended, Bioray Laboratories | Recruiting --> Suspended
Trial suspension
|
CD19 (CD19 Molecule)
|
cyclophosphamide • BRL-301
over2years
New P1 trial • CAR T-Cell Therapy
|
CD19 (CD19 Molecule)
|
CD19 positive
|
cyclophosphamide • BRL-301
over2years
U-CART: Safety and Efficacy Evaluation of CD19-UCART (clinicaltrials.gov)
P=N/A, N=20, Recruiting, Bioray Laboratories | Trial primary completion date: Dec 2021 --> Dec 2022
Trial primary completion date
|
CD19 (CD19 Molecule)
|
cyclophosphamide • BRL-301
almost4years
U-CART: Safety and Efficacy Evaluation of CD19-UCART (clinicaltrials.gov)
P=N/A, N=20, Recruiting, Bioray Laboratories | Trial completion date: Dec 2021 --> Dec 2022 | Trial primary completion date: Dec 2020 --> Dec 2021
Clinical • Trial completion date • Trial primary completion date
|
CD19 (CD19 Molecule)
|
BRL-301
over4years
U-CART: Safety and Efficacy Evaluation of CD19-UCART (clinicaltrials.gov)
P=N/A, N=20, Recruiting, Shanghai Bioray Laboratory Inc. | Trial primary completion date: Aug 2020 --> Dec 2020
Clinical • Trial primary completion date
|
CD19 (CD19 Molecule)
|
BRL-301