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DRUG:
Yescarta (axicabtagene ciloleucel)
i
Other names:
KTE-C19 CAR, anti-CD19 chimeric antigen receptor transduced T cells, KTEC19, KTE-C19, KTE-C19 chimeric antigen receptor T cell therapy, FKC876, FKC-876, anti-CD19-CAR PBL, anti-cluster of differentiation 19 (CD19)-CAR PBL, FKC 876
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Associations
(24)
News
Trials
Company:
Cabaret Biotech, Fosun Kite, Gilead, National Cancer Institute
Drug class:
CD19-targeted CAR-T immunotherapy
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obecabtagene autoleucel (1)
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pCAR-19B (1)
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T2 (0)
ALLO-501 (0)
AUTO1/22 (0)
AUTO3 (0)
Anti-CD19 CAR-T (0)
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CAR20.19.22 T (0)
CARCIK-CD19 (0)
CART-138/BCMA/19/more (0)
CART-19 (0)
CART-19/22 (0)
CD19 CAR T cells (0)
CD19 UCART cells (0)
CD19 and CD22 targeted prime CAR-T (0)
CD19 targeted CAR-T (0)
CD19-7×19 CAR-T (0)
CD19-CAR-DNT (0)
CD19-CAR-T2 cells (0)
CD19-CAR.CD45RA- negative T-cells (0)
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CD19-CD22 CAR-T (0)
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CD19.CAR-T (0)
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CD19/CD20 CAR T-cells (0)
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CD19/CD22 CAR-T cell therapy (0)
CD19/CD22 chimeric antigen receptor T cell (0)
CD19/CD22 dual-target CAR-T (0)
CD19/NKG2DL CAR-T Therapeutic (0)
CD19CAR/virus specific T cell therapy (0)
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CD22/CD19 CAR T (0)
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FT819 (0)
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GC007G (0)
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GC022F (0)
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HD-CAR-1 (0)
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LB1909 (0)
LCAR-AIO (0)
LstCAR019 (0)
MB-CAR-T19-22 (0)
MB-CART 19.1 (0)
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RPM CD19-mbIL15-CAR-T cells (0)
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SCRI-huCAR19v1 (0)
SCRI-huCAR19v2 (0)
SDS-19CAR (0)
SENL-B19 (0)
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STK-009/SYNCAR-001 (0)
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Senl 1904B (0)
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inaticabtagene autoleucel (0)
alloCART-19 cell therapy (0)
CRC01 (0)
anti-CD19 CAR-T cell therapy (0)
anti-CD19 CAR-T cell therapy (0)
anti-CD19 CAR-T therapy (0)
anti-CD19 DASH CAR-T (0)
anti-CD19-CAR (0)
anti-CD19-CAR γδT (0)
anti-CD19/CD22 CAR-T cells (0)
autologous 3rd generation CD19-targeting CAR T cell therapy (0)
autologous TriCAR T (0)
human derived (0)
huCART19 (0)
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human anti CD19 CAR-T cells (0)
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lisocabtagene maraleucel (23)
tisagenlecleucel-T (15)
brexucabtagene autoleucel (4)
CB-010 (2)
CTX110 (2)
relmacabtagene autoleucel (2)
IMPT-314 (2)
ISIKOK-19 (2)
PBCAR0191 (2)
AT101 (1)
ATA3219 (1)
AZD0120 (1)
obecabtagene autoleucel (1)
BRL-201 (1)
CAR-T19/CAR-T22 immunotherapy (1)
JCAR014 (1)
PZ01 (1)
ALLO-501A (1)
JNJ-4496 (1)
pCAR-19B (1)
ARI-0001 (1)
T2 (0)
ALLO-501 (0)
AUTO1/22 (0)
AUTO3 (0)
Anti-CD19 CAR-T (0)
Anti-CD19-CAR (0)
Anti-CD19/CD20/CD22 CAR T-Cells (0)
Autologous CAR-T cells (0)
BMS-986353 (0)
BRL-301 (0)
BZ019 (0)
BinD19 (0)
C-CAR011 (0)
CAR-20/19-T Cells (0)
CAR-T CD19/CD20/CD22/CD30 (0)
CAR19T2 T cells (0)
CAR20.19.22 T (0)
CARCIK-CD19 (0)
CART-138/BCMA/19/more (0)
CART-19 (0)
CART-19/22 (0)
CD19 CAR T cells (0)
CD19 UCART cells (0)
CD19 and CD22 targeted prime CAR-T (0)
CD19 targeted CAR-T (0)
CD19-7×19 CAR-T (0)
CD19-CAR-DNT (0)
CD19-CAR-T2 cells (0)
CD19-CAR.CD45RA- negative T-cells (0)
CD19-CAR_Lenti T cells (0)
CD19-CD22 CAR-T (0)
CD19-CD34 CAR transduced T cells (0)
CD19-CD34t metabolically programmed CAR transduced T-cells (0)
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CD19/BCMA targeted CAR T-cells (0)
CD19/CD20 CAR T-cells (0)
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CD19/CD22 CAR-T cell therapy (0)
CD19/CD22 chimeric antigen receptor T cell (0)
CD19/CD22 dual-target CAR-T (0)
CD19/NKG2DL CAR-T Therapeutic (0)
CD19CAR/virus specific T cell therapy (0)
CD19x22 CAR T (0)
CD20-CD19 cCAR T cells (0)
CD22/CD19 CAR T (0)
CLBR001/SWI019 (0)
CLIC-1901 (0)
CMV/CD19 bi-Specific CAR T (0)
CT032 (0)
CT120 (0)
CTA101 (0)
CTA30X UCAR-T (0)
CYAD-221 (0)
DDCAR-CD19 T-cells (0)
EGFRt/19-28z/4-1BBL CAR T cells (0)
ELI-011 (0)
ET 019003 (0)
ET-02 (0)
ET-901 (0)
FT819 (0)
GC007F (0)
GC007G (0)
GC019F (0)
GC022F (0)
GC502 (0)
GLPG5201 (0)
HD-CAR-1 (0)
HY004 (0)
IM19 CAR-T cells (0)
IMJ995 (0)
KITE-363 (0)
KUR-502 (0)
LB1909 (0)
LCAR-AIO (0)
LstCAR019 (0)
MB-CAR-T19-22 (0)
MB-CART 19.1 (0)
Meta10-19 (0)
OlyCAR-019 (0)
PBCAR19B (0)
PL001 (0)
RD133 (0)
RG6540 (0)
RPM CD19-mbIL15-CAR-T cells (0)
SC291 (0)
SCRI-CAR19 (0)
SCRI-CAR19x22v2 (0)
s (0)
SCRI-huCAR19v1 (0)
SCRI-huCAR19v2 (0)
SDS-19CAR (0)
SENL-B19 (0)
SJCAR19 (0)
SNUH-CD19-CAR-T (0)
STK-009/SYNCAR-001 (0)
Senl 1904A (0)
Senl 1904B (0)
Senl-h19 (0)
Senl_H19x22P (0)
TBI-1501 (0)
TT52CAR19 (0)
ThisCART19A (0)
UB-VV100 (0)
UCART19 (0)
UCD19 CAR T Cells (0)
UF-KURE19 (0)
WZTL-002 (0)
XYF19 CAR-T cells (0)
YTS101 (0)
inaticabtagene autoleucel (0)
alloCART-19 cell therapy (0)
CRC01 (0)
anti-CD19 CAR-T cell therapy (0)
anti-CD19 CAR-T cell therapy (0)
anti-CD19 CAR-T therapy (0)
anti-CD19 DASH CAR-T (0)
anti-CD19-CAR (0)
anti-CD19-CAR γδT (0)
anti-CD19/CD22 CAR-T cells (0)
autologous 3rd generation CD19-targeting CAR T cell therapy (0)
autologous TriCAR T (0)
human derived (0)
huCART19 (0)
huCART19-IL18 (0)
human anti CD19 CAR-T cells (0)
humanized CD19 CAR-T cell therapy (0)
iC9-CAR19 cells (0)
multi-CAR-T cell therapy (0)
multi-target gene-modified CAR-T/TCR-T cell immunotherapy (0)
murine CD19 CAR-T cell therapy (0)
murine autologous anti-CD19 CART cells (0)
YTB323 (0)
sequential different B cell antigen-targeted CAR T-cell therapy (0)
ssCART-19 (0)
JCAR015 (0)
MB-CART2019.1 (0)
›
Associations
(24)
News
Trials
VERI cancer hierarchy
Reset Filters
No biomarker
Follicular Lymphoma
No biomarker
Follicular Lymphoma
axicabtagene ciloleucel
Sensitive: A1 - Approval
axicabtagene ciloleucel
Sensitive
:
A1
axicabtagene ciloleucel
Sensitive: A1 - Approval
axicabtagene ciloleucel
Sensitive
:
A1
No biomarker
Diffuse Large B Cell Lymphoma
No biomarker
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Sensitive: A1 - Approval
axicabtagene ciloleucel
Sensitive
:
A1
axicabtagene ciloleucel
Sensitive: A1 - Approval
axicabtagene ciloleucel
Sensitive
:
A1
No biomarker
Mediastinal B Cell Lymphoma
No biomarker
Mediastinal B Cell Lymphoma
axicabtagene ciloleucel
Sensitive: A1 - Approval
axicabtagene ciloleucel
Sensitive
:
A1
axicabtagene ciloleucel
Sensitive: A1 - Approval
axicabtagene ciloleucel
Sensitive
:
A1
No biomarker
Lymphoma
No biomarker
Lymphoma
axicabtagene ciloleucel
Resistant: A1 - Approval
axicabtagene ciloleucel
Resistant
:
A1
axicabtagene ciloleucel
Resistant: A1 - Approval
axicabtagene ciloleucel
Resistant
:
A1
No biomarker
Marginal Zone Lymphoma
No biomarker
Marginal Zone Lymphoma
axicabtagene ciloleucel
Sensitive: A2 - Guideline
axicabtagene ciloleucel
Sensitive
:
A2
axicabtagene ciloleucel
Sensitive: A2 - Guideline
axicabtagene ciloleucel
Sensitive
:
A2
MYC positive + BCL2 positive
Diffuse Large B Cell Lymphoma
MYC positive + BCL2 positive
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
MYC positive + BCL2 positive + BCL6 positive
Diffuse Large B Cell Lymphoma
MYC positive + BCL2 positive + BCL6 positive
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
MYC overexpression + BCL2 overexpression
Diffuse Large B Cell Lymphoma
MYC overexpression + BCL2 overexpression
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
PAX5 mutation
Diffuse Large B Cell Lymphoma
PAX5 mutation
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
IRF8 mutation
Diffuse Large B Cell Lymphoma
IRF8 mutation
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
CD19 mutation
Diffuse Large B Cell Lymphoma
CD19 mutation
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
CD58 mutation
Diffuse Large B Cell Lymphoma
CD58 mutation
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
TP53 mutation
Diffuse Large B Cell Lymphoma
TP53 mutation
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
LDH elevation
Lymphoma
LDH elevation
Lymphoma
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
IL6 elevation
Diffuse Large B Cell Lymphoma
IL6 elevation
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
LDH elevation
Diffuse Large B Cell Lymphoma
LDH elevation
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
CXCL8 elevation
Diffuse Large B Cell Lymphoma
CXCL8 elevation
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
CCL4 elevation
Diffuse Large B Cell Lymphoma
CCL4 elevation
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
IL27 elevation
Diffuse Large B Cell Lymphoma
IL27 elevation
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
axicabtagene ciloleucel
Resistant: C3 – Early Trials
axicabtagene ciloleucel
Resistant
:
C3
CD19 positive
Follicular Lymphoma
CD19 positive
Follicular Lymphoma
acalabrutinib + axicabtagene ciloleucel
Sensitive: C3 – Early Trials
acalabrutinib + axicabtagene ciloleucel
Sensitive
:
C3
acalabrutinib + axicabtagene ciloleucel
Sensitive: C3 – Early Trials
acalabrutinib + axicabtagene ciloleucel
Sensitive
:
C3
CD19 positive
Diffuse Large B Cell Lymphoma
CD19 positive
Diffuse Large B Cell Lymphoma
acalabrutinib + axicabtagene ciloleucel
Sensitive: C3 – Early Trials
acalabrutinib + axicabtagene ciloleucel
Sensitive
:
C3
acalabrutinib + axicabtagene ciloleucel
Sensitive: C3 – Early Trials
acalabrutinib + axicabtagene ciloleucel
Sensitive
:
C3
MYC rearrangement + BCL2 rearrangement + BCL6 rearrangement
Diffuse Large B Cell Lymphoma
MYC rearrangement + BCL2 rearrangement + BCL6 rearrangement
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
MYC rearrangement + BCL6 rearrangement
Diffuse Large B Cell Lymphoma
MYC rearrangement + BCL6 rearrangement
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
axicabtagene ciloleucel
Sensitive: C3 – Early Trials
axicabtagene ciloleucel
Sensitive
:
C3
^
^
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