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DRUG:

Tecartus (brexucabtagene autoleucel)

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Company:

Fosun Kite, Gilead

Drug class:

CD19-targeted CAR-T immunotherapy

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MB-CART2019.1 (0)

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CD19 CAR T cells (0)

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autologous 3rd generation CD19-targeting CAR T cell therapy (0)

autologous TriCAR T (0)

human derived (0)

huCART19-IL18 (0)

human anti CD19 CAR-T cells (0)

humanized CD19 CAR-T cell therapy (0)

humanized CD19 CAR-T cells (0)

iC9-CAR19 cells (0)

multi-CAR-T cell therapy (0)

multi-target gene-modified CAR-T/TCR-T cell immunotherapy (0)

murine CD19 CAR-T cell therapy (0)

murine autologous anti-CD19 CART cells (0)

sequential different B cell antigen-targeted CAR T-cell therapy (0)

MB-CART2019.1 (0)

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No biomarker	Mantle Cell Lymphoma	No biomarker	Mantle Cell Lymphoma	brexucabtagene autoleucel Sensitive: A1 - Approval brexucabtagene autoleucel Sensitive : A1	brexucabtagene autoleucel Sensitive: A1 - Approval brexucabtagene autoleucel Sensitive : A1
No biomarker	B Acute Lymphoblastic Leukemia	No biomarker	B Acute Lymphoblastic Leukemia	brexucabtagene autoleucel Sensitive: A1 - Approval brexucabtagene autoleucel Sensitive : A1	brexucabtagene autoleucel Sensitive: A1 - Approval brexucabtagene autoleucel Sensitive : A1
BCR-ABL1 fusion	B Acute Lymphoblastic Leukemia	BCR-ABL1 fusion	B Acute Lymphoblastic Leukemia	brexucabtagene autoleucel Sensitive: A2 - Guideline brexucabtagene autoleucel Sensitive : A2	brexucabtagene autoleucel Sensitive: A2 - Guideline brexucabtagene autoleucel Sensitive : A2
CCR7 positive	Mantle Cell Lymphoma	CCR7 positive	Mantle Cell Lymphoma	brexucabtagene autoleucel Sensitive: B - Late Trials brexucabtagene autoleucel Sensitive : B	brexucabtagene autoleucel Sensitive: B - Late Trials brexucabtagene autoleucel Sensitive : B