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DRUG:

CD19-CAR.CD45RA- negative T-cells

i
Other names: CD19-CAR.CD45RA- negative T-cells, CD19-directed allogeneic memory T-cell therapy, CD19-CAR(Mem) T-cells, CD19-CAR.CD45RA-negative T-cells
Associations
Trials
Company:
St. Jude Children's Research Hospital
Drug class:
CD19-targeted CAR-T immunotherapy
Related drugs:
Associations
Trials
9ms
Study of CD19-directed Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia (clinicaltrials.gov)
P1, N=60, Recruiting, St. Jude Children's Research Hospital | Trial completion date: Jan 2026 --> Jun 2027 | Trial primary completion date: Jan 2025 --> Jun 2026
Trial completion date • Trial primary completion date
|
CD19 positive
|
cyclophosphamide • fludarabine IV • CD19-CAR.CD45RA- negative T-cells
over3years
Clinical • New P1 trial
|
CD19 (CD19 Molecule)
|
CD19 positive
|
fludarabine IV • mesna • CD19-CAR.CD45RA- negative T-cells • cyclophosphamide intravenous