COMPANY:

Protean BioDiagnostics

"Arima Genomics, Inc...announced an agreement to make an Arima next-generation sequencing-based test available to clinicians for patient management through Protean BioDiagnostic’s CLIA-certified, CAP-accredited laboratory in Orlando, Florida. The new testing service, using Arima’s novel genomic technology, will identify clinically actionable gene fusions in tumor tissue from patients with cancer, and is anticipated to be available for order in the first half of 2023."

"...presenting two case studies this year at AMP 22, on the use of DelPHI, Protean MAPS, and Navify Digital Tools for the timely diagnosis and/or treatment of cancer...systematic approach that combines molecular testing with digital decision support tools to diagnose a child’s ES and identify viable therapy options."

"Protean BioDiagnostics will be presenting a case study this year at AMP 22, on the topic of the importance of precision medicine in uncovering a patient’s true diagnosis...This is a case study that highlights the power of Protean to catch a liver carcinoma misdiagnosis using pathology review, comprehensive in-house molecular testing, and virtual molecular tumor boards."

"Protean BioDiagnostics and Qualisure Diagnostics Inc. announced...that both companies have entered into a strategic partnership to launch a novel diagnostic test for thyroid cancer. Thyroid GuidePx® is the first genomic classifier for papillary thyroid cancer, designed to assist clinicians treating thyroid cancer in making treatment decisions."

"Protean BioDiagnostics to present on the use of optical genome mapping and NGS to understand epitheliod sarcoma in a pediatric patient...Combining traditional next generation sequencing with optical genome mapping presents a robust picture of the precise genomic alterations. Evidence of these specific structural alterations combined with immunohistochemistry provides clinically relevant variants for genetic disease, which can be utilized to identify actionable targets for therapy, and more optimal outcome for the patient."

"Protean BioDiagnostics to present on embryonal rhabdomyosarcoma in a pediatric patient...Combining immunohistochemistry, OncoTargets pathway analysis that measures key signaling pathway activity, Follow It liquid biopsy, and structural chromosome aberration analysis by copy number variation uncovered that this patient was eligible for a novel clinical trial containing MEK and PD-L1 checkpoint inhibitors."

"Experts from Protean BioDiagnostics will present ground breaking research focused on identifying the molecular basis of colorectal cancer and how it differs between men and women in America at the AACR 2022 meeting in New Orleans...The findings have implications for designing effective screening and treatments which may need to be adjusted based on the gender of the subject."

"Protean BioDiagnostics presents a new method to identify potential therapeutic targets in breast cancer...The method called OncoSignal analysis utilizes mRNA transcriptional measurements to accurately calculate the pathway activity of seven key oncogenic signaling pathways."

"Protean BioDiagnostics present...study entitled 'Distinct and targetable molecular features of breast cancer in African American women' which was aimed at determining if breast cancer occurring in African American women might have different molecular features...The study evaluated data from the Cancer Genome atlas project and data from recent clinical trials. Bioinformatic analysis revealed that cancers occurring in African American women have a distinct molecular profile than those occurring in Caucasian women."