vincristine

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Company:

Generic mfg.

Drug class:

Tubulin polymerization inhibitor

Related drugs:

No biomarker	Medulloblastoma	No biomarker	Medulloblastoma	cisplatin + cyclophosphamide + vincristine Sensitive: A2 - Guideline cisplatin + cyclophosphamide + vincristine Sensitive : A2	cisplatin + cyclophosphamide + vincristine Sensitive: A2 - Guideline cisplatin + cyclophosphamide + vincristine Sensitive : A2
No biomarker	Medulloblastoma	No biomarker	Medulloblastoma	cisplatin + vincristine + lomustine Sensitive: A2 - Guideline cisplatin + vincristine + lomustine Sensitive : A2	cisplatin + vincristine + lomustine Sensitive: A2 - Guideline cisplatin + vincristine + lomustine Sensitive : A2
No biomarker	Acute Lymphocytic Leukemia	No biomarker	Acute Lymphocytic Leukemia	vincristine + prednisone Sensitive: A2 - Guideline vincristine + prednisone Sensitive : A2	vincristine + prednisone Sensitive: A2 - Guideline vincristine + prednisone Sensitive : A2
No biomarker	Childhood B Acute Lymphoblastic Leukemia	No biomarker	Childhood B Acute Lymphoblastic Leukemia	cytarabine + cyclophosphamide + methotrexate + vincristine + pegaspargase Sensitive: A2 - Guideline cytarabine + cyclophosphamide + methotrexate + vincristine + pegaspargase Sensitive : A2	cytarabine + cyclophosphamide + methotrexate + vincristine + pegaspargase Sensitive: A2 - Guideline cytarabine + cyclophosphamide + methotrexate + vincristine + pegaspargase Sensitive : A2
No biomarker	Childhood B Acute Lymphoblastic Leukemia	No biomarker	Childhood B Acute Lymphoblastic Leukemia	vincristine + dexamethasone + mitoxantrone + pegaspargase Sensitive: A2 - Guideline vincristine + dexamethasone + mitoxantrone + pegaspargase Sensitive : A2	vincristine + dexamethasone + mitoxantrone + pegaspargase Sensitive: A2 - Guideline vincristine + dexamethasone + mitoxantrone + pegaspargase Sensitive : A2
No biomarker	Rhabdomyosarcoma	No biomarker	Rhabdomyosarcoma	doxorubicin hydrochloride + cyclophosphamide + etoposide IV + vincristine Sensitive: A2 - Guideline doxorubicin hydrochloride + cyclophosphamide + etoposide IV + vincristine Sensitive : A2	doxorubicin hydrochloride + cyclophosphamide + etoposide IV + vincristine Sensitive: A2 - Guideline doxorubicin hydrochloride + cyclophosphamide + etoposide IV + vincristine Sensitive : A2
No biomarker	Rhabdomyosarcoma	No biomarker	Rhabdomyosarcoma	temozolomide + irinotecan + vincristine Sensitive: A2 - Guideline temozolomide + irinotecan + vincristine Sensitive : A2	temozolomide + irinotecan + vincristine Sensitive: A2 - Guideline temozolomide + irinotecan + vincristine Sensitive : A2
No biomarker	Rhabdomyosarcoma	No biomarker	Rhabdomyosarcoma	vincristine + dactinomycin Sensitive: A2 - Guideline vincristine + dactinomycin Sensitive : A2	vincristine + dactinomycin Sensitive: A2 - Guideline vincristine + dactinomycin Sensitive : A2
No biomarker	Rhabdomyosarcoma	No biomarker	Rhabdomyosarcoma	irinotecan + vincristine Sensitive: A2 - Guideline irinotecan + vincristine Sensitive : A2	irinotecan + vincristine Sensitive: A2 - Guideline irinotecan + vincristine Sensitive : A2
No biomarker	Rhabdomyosarcoma	No biomarker	Rhabdomyosarcoma	doxorubicin hydrochloride + ifosfamide + vincristine Sensitive: A2 - Guideline doxorubicin hydrochloride + ifosfamide + vincristine Sensitive : A2	doxorubicin hydrochloride + ifosfamide + vincristine Sensitive: A2 - Guideline doxorubicin hydrochloride + ifosfamide + vincristine Sensitive : A2
No biomarker	Rhabdomyosarcoma	No biomarker	Rhabdomyosarcoma	doxorubicin hydrochloride + cyclophosphamide + ifosfamide + vincristine Sensitive: A2 - Guideline doxorubicin hydrochloride + cyclophosphamide + ifosfamide + vincristine Sensitive : A2	doxorubicin hydrochloride + cyclophosphamide + ifosfamide + vincristine Sensitive: A2 - Guideline doxorubicin hydrochloride + cyclophosphamide + ifosfamide + vincristine Sensitive : A2
No biomarker	Ewing Sarcoma	No biomarker	Ewing Sarcoma	temozolomide + irinotecan + vincristine Sensitive: A2 - Guideline temozolomide + irinotecan + vincristine Sensitive : A2	temozolomide + irinotecan + vincristine Sensitive: A2 - Guideline temozolomide + irinotecan + vincristine Sensitive : A2
No biomarker	Acute Lymphocytic Leukemia	No biomarker	Acute Lymphocytic Leukemia	vincristine + prednisone + daunorubicin + pegaspargase Sensitive: A2 - Guideline vincristine + prednisone + daunorubicin + pegaspargase Sensitive : A2	vincristine + prednisone + daunorubicin + pegaspargase Sensitive: A2 - Guideline vincristine + prednisone + daunorubicin + pegaspargase Sensitive : A2
No biomarker	T Acute Lymphoblastic Leukemia	No biomarker	T Acute Lymphoblastic Leukemia	vincristine + prednisone + daunorubicin + pegaspargase + nelarabine Sensitive: A2 - Guideline vincristine + prednisone + daunorubicin + pegaspargase + nelarabine Sensitive : A2	vincristine + prednisone + daunorubicin + pegaspargase + nelarabine Sensitive: A2 - Guideline vincristine + prednisone + daunorubicin + pegaspargase + nelarabine Sensitive : A2
No biomarker	Astrocytoma	No biomarker	Astrocytoma	carboplatin + vincristine Sensitive: A2 - Guideline carboplatin + vincristine Sensitive : A2	carboplatin + vincristine Sensitive: A2 - Guideline carboplatin + vincristine Sensitive : A2
No biomarker	B Acute Lymphoblastic Leukemia	No biomarker	B Acute Lymphoblastic Leukemia	vincristine + prednisone + daunorubicin + pegaspargase Sensitive: A2 - Guideline vincristine + prednisone + daunorubicin + pegaspargase Sensitive : A2	vincristine + prednisone + daunorubicin + pegaspargase Sensitive: A2 - Guideline vincristine + prednisone + daunorubicin + pegaspargase Sensitive : A2
No biomarker	B Acute Lymphoblastic Leukemia	No biomarker	B Acute Lymphoblastic Leukemia	Tyrosine kinase inhibitor + vincristine + dexamethasone Sensitive: A2 - Guideline Tyrosine kinase inhibitor + vincristine + dexamethasone Sensitive : A2	Tyrosine kinase inhibitor + vincristine + dexamethasone Sensitive: A2 - Guideline Tyrosine kinase inhibitor + vincristine + dexamethasone Sensitive : A2
Chr del(1p)+ Chr del(19q)	Glioma	Chr del(1p)+ Chr del(19q)	Glioma	vincristine + lomustine + procarbazine hydrochloride Sensitive: C3 – Early Trials vincristine + lomustine + procarbazine hydrochloride Sensitive : C3	vincristine + lomustine + procarbazine hydrochloride Sensitive: C3 – Early Trials vincristine + lomustine + procarbazine hydrochloride Sensitive : C3
Chr del(1p)	Glioma	Chr del(1p)	Glioma	vincristine + lomustine + procarbazine hydrochloride Sensitive: C3 – Early Trials vincristine + lomustine + procarbazine hydrochloride Sensitive : C3	vincristine + lomustine + procarbazine hydrochloride Sensitive: C3 – Early Trials vincristine + lomustine + procarbazine hydrochloride Sensitive : C3
CDKN2A deletion	Glioma	CDKN2A deletion	Glioma	vincristine + lomustine + procarbazine hydrochloride Resistant: C3 – Early Trials vincristine + lomustine + procarbazine hydrochloride Resistant : C3	vincristine + lomustine + procarbazine hydrochloride Resistant: C3 – Early Trials vincristine + lomustine + procarbazine hydrochloride Resistant : C3
ETV6-NTRK3 fusion	Fibrosarcoma	ETV6-NTRK3 fusion	Fibrosarcoma	vincristine + dactinomycin Resistant: C4 – Case Studies vincristine + dactinomycin Resistant : C4	vincristine + dactinomycin Resistant: C4 – Case Studies vincristine + dactinomycin Resistant : C4
IDH1 R132S + H3K27me3 loss + MET exon 14 skipping mutation	Anaplastic Astrocytoma	IDH1 R132S + H3K27me3 loss + MET exon 14 skipping mutation	Anaplastic Astrocytoma	carboplatin + temozolomide + vincristine Resistant: C4 – Case Studies carboplatin + temozolomide + vincristine Resistant : C4	carboplatin + temozolomide + vincristine Resistant: C4 – Case Studies carboplatin + temozolomide + vincristine Resistant : C4
NF1 deletion	Breast Cancer	NF1 deletion	Breast Cancer	vincristine Sensitive: D – Preclinical vincristine Sensitive : D	vincristine Sensitive: D – Preclinical vincristine Sensitive : D
PGP expression	Glioblastoma	PGP expression	Glioblastoma	vincristine Resistant: D – Preclinical vincristine Resistant : D	vincristine Resistant: D – Preclinical vincristine Resistant : D
CYP3A4 overexpression	Soft Tissue Sarcoma	CYP3A4 overexpression	Soft Tissue Sarcoma	vincristine Resistant: D – Preclinical vincristine Resistant : D	vincristine Resistant: D – Preclinical vincristine Resistant : D

vincristine

Associations
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Associations
(25)

vincristine

Associations(25)

Associations(25)

Associations
(25)

Associations
(25)