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Association details:
| Biomarker: | No biomarker |
|---|---|
| Cancer: | Childhood B Acute Lymphoblastic Leukemia |
| Drug: | cytarabine (DNA synthesis inhibitor, DNA-directed DNAP inhibitor) + cyclophosphamide (Alkylating agent) + methotrexate (THF dehydrogenase inhibitor, Dihydrofolic acid reductase inhibitor) + vincristine (Tubulin polymerization inhibitor) + Oncaspar liquid (pegaspargase) (Asparagine depleter, Aspartate-ammonia ligase inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Excerpt:
Pediatric Acute Lymphoblastic Leukemia: Other Recommended regimens…BFM Intensification Block 1: high-dose methotrexate, high-dose cytarabine, dexamethasone, vincristine, pegaspargase, and cyclophosphamide
