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BIOMARKER:

TP53 wild-type

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Other names: TP53, Tumor Protein P53, Cellular Tumor Antigen P53, Phosphoprotein P53, Tumor Protein P53, Antigen NY-CO-13, Transformation-Related Protein 53, Mutant Tumor Protein 53, P53 Tumor Suppressor, Tumor Suppressor P53, Tumor Protein 53, BMFS5, TRP53, BCC7, LFS1
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Entrez ID:
TP53 wild-type
Myelodysplastic Syndrome
GS-4721
Sensitive
:
C3
SOHO 2022 - 5 days - (New C3)
TP53 wild-type
Solid Tumor
BI 907828
Sensitive
:
C2
ESMO 2022 - 3 weeks - (New C3)
TP53 wild-type
Small Lymphocytic Lymphoma
PCR
Sensitive
:
A2
TP53 wild-type
Small Lymphocytic Lymphoma
FCR
Sensitive
:
A2
TP53 wild-type
Small Lymphocytic Lymphoma
alemtuzumab
Sensitive
:
A2
TP53 wild-type
Small Lymphocytic Lymphoma
rituximab
Sensitive
:
A2
TP53 wild-type
Small Lymphocytic Lymphoma
chlorambucil
Sensitive
:
A2
TP53 wild-type
Small Lymphocytic Lymphoma
venetoclax + obinutuzumab
Sensitive
:
A2
TP53 wild-type
Small Lymphocytic Lymphoma
CD20 inhibitor
Sensitive
:
A2
TP53 wild-type
Small Lymphocytic Lymphoma
rituximab + idelalisib
Sensitive
:
A2
TP53 wild-type
Small Lymphocytic Lymphoma
obinutuzumab + acalabrutinib
Sensitive
:
A2
TP53 wild-type
Small Lymphocytic Lymphoma
ibrutinib + obinutuzumab
Sensitive
:
A2
TP53 wild-type
Small Lymphocytic Lymphoma
zanubrutinib
Sensitive
:
A2
TP53 wild-type
Small Lymphocytic Lymphoma
rituximab + ibrutinib
Sensitive
:
A2
TP53 wild-type
Chronic Lymphocytic Leukemia
zanubrutinib
Sensitive
:
A2
TP53 wild-type
Chronic Lymphocytic Leukemia
venetoclax
Sensitive
:
A2
TP53 wild-type
Acute Myelogenous Leukemia
RO5503781
Resistant
:
B
TP53 wild-type
Endometrial Cancer
selinexor
Sensitive
:
B
TP53 wild-type
Lymphoma
ALRN-6924
Sensitive
:
C2
TP53 wild-type
Solid Tumor
ALRN-6924
Sensitive
:
C2
TP53 wild-type
Solid Tumor
KRT-232
Sensitive
:
C2
TP53 wild-type
Estrogen Receptor Positive Breast Cancer
ALRN-6924
Sensitive
:
C2
TP53 wild-type
Acute Myelogenous Leukemia
HDM201
Sensitive
:
C3
TP53 wild-type
Solid Tumor
HDM201
Sensitive
:
C3
TP53 wild-type
Liposarcoma
MK-8242
Sensitive
:
C3
TP53 wild-type
Solid Tumor
MK-8242
Sensitive
:
C3
TP53 wild-type
Multiple Myeloma
KRT-232
Sensitive
:
C3
TP53 wild-type
Liposarcoma
HDM201
Sensitive
:
C3
TP53 wild-type
Merkel Cell Carcinoma
KRT-232
Sensitive
:
C3
TP53 wild-type
Melanoma
trametinib + dabrafenib + KRT-232
Sensitive
:
C3
TP53 wild-type
Acute Myelogenous Leukemia
venetoclax
Sensitive
:
C3
TP53 wild-type
Breast Cancer
selinexor + chidamide
Sensitive
:
D
TP53 wild-type
Breast Cancer
chidamide
Sensitive
:
D
TP53 wild-type
Acute Myelogenous Leukemia
thioureidobutyronitrile
Sensitive
:
D