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Association details:
Biomarker:
TP53 wild-type
Cancer:
Small Lymphocytic Lymphoma
Drug:
Imbruvica (ibrutinib)
(
BTK inhibitor
) +
Gazyva (obinutuzumab)
(
CD20 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
Chronic lymphocytic leukemia/Small lymphocytic lymphoma...CLL/SLL without del(17p)/TP53 mutation...First-line therapy…Other recommended regimens…ibrutinib + obinutuzumab (category 2B).
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