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Association details:
Biomarker:
TP53 wild-type
Cancer:
Small Lymphocytic Lymphoma
Drug:
Gazyva (obinutuzumab)
(
CD20 inhibitor
) +
Calquence (acalabrutinib)
(
BTK inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
CLL/SLL without del(17p)/TP53 mutation, First-line therapy, Frail patient with significant comorbidity…Acalabrutinib ± obinutuzumab was changed from a category 2A recommendation to a category 1 recommendation.
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