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BIOMARKER:
TP53 mutation + MDM2 mutation
i
Other names:
TP53, Tumor Protein P53, Cellular Tumor Antigen P53, Phosphoprotein P53, Tumor Protein P53, Antigen NY-CO-13, Transformation-Related Protein 53, Mutant Tumor Protein 53, P53 Tumor Suppressor, Tumor Suppressor P53, Tumor Protein 53, BMFS5, TRP53, BCC7, LFS1, MDM2, HDM2, MGC5370, MDM2 proto-oncogene, E3 ubiquitin protein ligase
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Entrez ID:
7157
;
4193
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
TP53 deletion (21)
MDM2 amplification (21)
LPL deletion + TP53 deletion (1)
TP53 amplification (1)
FRS2 amplification + MDM2 amplification (1)
MDM2 amplification + CDK4 amplification (1)
MDM2 amplification + TWIST1 amplification (1)
TP53 deletion (21)
MDM2 amplification (21)
LPL deletion + TP53 deletion (1)
TP53 amplification (1)
FRS2 amplification + MDM2 amplification (1)
MDM2 amplification + CDK4 amplification (1)
MDM2 amplification + TWIST1 amplification (1)
›
Associations
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VERI cancer hierarchy
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TP53 mutation + MDM2 mutation
Urothelial Cancer
TP53 mutation + MDM2 mutation
Urothelial Cancer
sacituzumab govitecan-hziy
Sensitive: C3 – Early Trials
sacituzumab govitecan-hziy
Sensitive
:
C3
sacituzumab govitecan-hziy
Sensitive: C3 – Early Trials
sacituzumab govitecan-hziy
Sensitive
:
C3
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