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BIOMARKER:

TP53 deletion

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Other names: TP53, Tumor Protein P53, Cellular Tumor Antigen P53, Phosphoprotein P53, Tumor Protein P53, Antigen NY-CO-13, Transformation-Related Protein 53, Mutant Tumor Protein 53, P53 Tumor Suppressor, Tumor Suppressor P53, Tumor Protein 53, BMFS5, TRP53, BCC7, LFS1
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Entrez ID:
TP53 deletion
Chronic Lymphocytic Leukemia
idelalisib
Sensitive
:
A2
TP53 deletion
Chronic Lymphocytic Leukemia
ibrutinib
Sensitive
:
A2
TP53 deletion
Chronic Lymphocytic Leukemia
rituximab
Sensitive
:
A2
TP53 deletion
Small Lymphocytic Lymphoma
ibrutinib
Sensitive
:
A2
TP53 deletion
Prostate Cancer
abiraterone acetate
Resistant
:
B
TP53 deletion
Prostate Cancer
enzalutamide capsule
Resistant
:
B
TP53 deletion
Chronic Lymphocytic Leukemia
venetoclax + obinutuzumab
Sensitive
:
C2
TP53 deletion
Melanoma
Immunotherapy
Resistant
:
C3
TP53 deletion
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive
:
C3
TP53 deletion
Mantle Cell Lymphoma
venetoclax + rituximab + ibrutinib
Sensitive
:
C3
TP53 deletion
Chronic Lymphocytic Leukemia
ONC212
Sensitive
:
D
TP53 deletion
Colorectal Cancer
sirolimus + IPI-504
Sensitive
:
D
TP53 deletion
Non Small Cell Lung Cancer
sirolimus + IPI-504
Sensitive
:
D
TP53 deletion
Mantle Cell Lymphoma
venetoclax
Resistant
:
D