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BIOMARKER:

MDM2 amplification

i
Other names: MDM2, HDM2, MGC5370, MDM2 proto-oncogene, E3 ubiquitin protein ligase
Entrez ID:
Related biomarkers:
MDM2 amplification
Diffuse Large B Cell Lymphoma
R-CHOP
Resistant: C3 – Early Trials
Br J Haematol - 1 week
MDM2 amplification
Liposarcoma
APG-115
Sensitive: C2 – Inclusion Criteria
MDM2 amplification
Solid Tumor
RAIN-32
Sensitive: C2 – Inclusion Criteria
MDM2 amplification
Liposarcoma
RAIN-32
Sensitive: C2 – Inclusion Criteria
MDM2 amplification
Mucosal Melanoma
ipilimumab
Resistant: C3 – Early Trials
MDM2 amplification
Mucosal Melanoma
nivolumab + ipilimumab
Resistant: C3 – Early Trials
MDM2 amplification
Mucosal Melanoma
nivolumab
Resistant: C3 – Early Trials
MDM2 amplification
Mucosal Melanoma
pembrolizumab
Resistant: C3 – Early Trials
MDM2 amplification
Gastric Adenocarcinoma
Immunotherapy
Resistant: C3 – Early Trials
MDM2 amplification
Liposarcoma
BI 907828
Sensitive: C3 – Early Trials
MDM2 amplification
Sarcoma
RAIN-32
Sensitive: C3 – Early Trials
MDM2 amplification
Triple Negative Breast Cancer
pembrolizumab
Resistant: C4 – Case Studies