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BIOMARKER:
RET rearrangement
i
Other names:
RET, Ret Proto-Oncogene, Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret, Cadherin-Related Family Member 16, Rearranged During Transfection, RET Receptor Tyrosine Kinase, Cadherin Family Member 12, Proto-Oncogene C-Ret, CDHF12, CDHR16, PTC, Ret Proto-Oncogene (Multiple Endocrine Neoplasia And Medullary Thyroid Carcinoma 1, Hirschsprung Disease), Multiple Endocrine Neoplasia And Medullary Thyroid Carcinoma 1, Hirschsprung Disease 1, RET-ELE1, HSCR1, MEN2A, MEN2B, RET51, MTC1
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Entrez ID:
5979
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
RET mutation (20)
RET M918T (12)
RET C634W (9)
RET-PTC1 rearrangement (8)
RET C634R (4)
RET C634Y (2)
RET G810C (2)
RET G810D (2)
RET G810R (2)
RET G810S (2)
RET G810V (2)
RET L629P (2)
RET V804L (2)
RET V804M (2)
BRAF V600E + TERT E441del + RET N579K + EZH2 D154E + CDK4 S259L (1)
RET C618R (1)
RET C620R (1)
RET C634* (1)
RET C634F (1)
RET D631_R635delinsG (1)
RET M918T + ATM L804fs*4 + ATM S978fs*12 (1)
RET V637R (1)
RET V804* (1)
RET V804M + M918T (1)
RET V804M + RET M918T + RET G810 + RET Y806 (1)
RET Y900_S904delinsP (1)
RET wild-type (1)
RET mutation (20)
RET M918T (12)
RET C634W (9)
RET-PTC1 rearrangement (8)
RET C634R (4)
RET C634Y (2)
RET G810C (2)
RET G810D (2)
RET G810R (2)
RET G810S (2)
RET G810V (2)
RET L629P (2)
RET V804L (2)
RET V804M (2)
BRAF V600E + TERT E441del + RET N579K + EZH2 D154E + CDK4 S259L (1)
RET C618R (1)
RET C620R (1)
RET C634* (1)
RET C634F (1)
RET D631_R635delinsG (1)
RET M918T + ATM L804fs*4 + ATM S978fs*12 (1)
RET V637R (1)
RET V804* (1)
RET V804M + M918T (1)
RET V804M + RET M918T + RET G810 + RET Y806 (1)
RET Y900_S904delinsP (1)
RET wild-type (1)
›
Associations
News
Trials
VERI cancer hierarchy
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RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
cabozantinib tablet
Sensitive: A2 - Guideline
cabozantinib tablet
Sensitive
:
A2
cabozantinib tablet
Sensitive: A2 - Guideline
cabozantinib tablet
Sensitive
:
A2
RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
selpercatinib
Sensitive: A2 - Guideline
selpercatinib
Sensitive
:
A2
selpercatinib
Sensitive: A2 - Guideline
selpercatinib
Sensitive
:
A2
RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
pralsetinib
Sensitive: A2 - Guideline
pralsetinib
Sensitive
:
A2
pralsetinib
Sensitive: A2 - Guideline
pralsetinib
Sensitive
:
A2
RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
alectinib
Sensitive: C2 – Inclusion Criteria
alectinib
Sensitive
:
C2
alectinib
Sensitive: C2 – Inclusion Criteria
alectinib
Sensitive
:
C2
RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
sunitinib
Sensitive: C2 – Inclusion Criteria
sunitinib
Sensitive
:
C2
sunitinib
Sensitive: C2 – Inclusion Criteria
sunitinib
Sensitive
:
C2
RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
vandetanib
Sensitive: C3 – Early Trials
vandetanib
Sensitive
:
C3
vandetanib
Sensitive: C3 – Early Trials
vandetanib
Sensitive
:
C3
RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
selpercatinib + pralsetinib
Sensitive: C3 – Early Trials
selpercatinib + pralsetinib
Sensitive
:
C3
selpercatinib + pralsetinib
Sensitive: C3 – Early Trials
selpercatinib + pralsetinib
Sensitive
:
C3
RET rearrangement
Lung Adenocarcinoma
RET rearrangement
Lung Adenocarcinoma
cabozantinib tablet
Sensitive: C3 – Early Trials
cabozantinib tablet
Sensitive
:
C3
cabozantinib tablet
Sensitive: C3 – Early Trials
cabozantinib tablet
Sensitive
:
C3
RET rearrangement
Thyroid Gland Carcinoma
RET rearrangement
Thyroid Gland Carcinoma
selumetinib
Sensitive: D – Preclinical
selumetinib
Sensitive
:
D
selumetinib
Sensitive: D – Preclinical
selumetinib
Sensitive
:
D
RET rearrangement
Thyroid Gland Papillary Carcinoma
RET rearrangement
Thyroid Gland Papillary Carcinoma
MK-2206
Sensitive: D – Preclinical
MK-2206
Sensitive
:
D
MK-2206
Sensitive: D – Preclinical
MK-2206
Sensitive
:
D
RET rearrangement
Thyroid Gland Carcinoma
RET rearrangement
Thyroid Gland Carcinoma
AZD1480
Sensitive: D – Preclinical
AZD1480
Sensitive
:
D
AZD1480
Sensitive: D – Preclinical
AZD1480
Sensitive
:
D
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