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BIOMARKER:
RET rearrangement
i
Other names:
RET, Ret Proto-Oncogene, Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret, Cadherin-Related Family Member 16, Rearranged During Transfection, RET Receptor Tyrosine Kinase, Cadherin Family Member 12, Proto-Oncogene C-Ret, CDHF12, CDHR16, PTC, Ret Proto-Oncogene (Multiple Endocrine Neoplasia And Medullary Thyroid Carcinoma 1, Hirschsprung Disease), Multiple Endocrine Neoplasia And Medullary Thyroid Carcinoma 1, Hirschsprung Disease 1, RET-ELE1, HSCR1, MEN2A, MEN2B, RET51, MTC1
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Entrez ID:
5979
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
RET overexpression (3)
RET expression (1)
RET positive (1)
RET positive + PD-L1 overexpression (1)
RET overexpression (3)
RET expression (1)
RET positive (1)
RET positive + PD-L1 overexpression (1)
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RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
cabozantinib tablet
Sensitive: A2 - Guideline
cabozantinib tablet
Sensitive
:
A2
cabozantinib tablet
Sensitive: A2 - Guideline
cabozantinib tablet
Sensitive
:
A2
RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
selpercatinib
Sensitive: A2 - Guideline
selpercatinib
Sensitive
:
A2
selpercatinib
Sensitive: A2 - Guideline
selpercatinib
Sensitive
:
A2
RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
pralsetinib
Sensitive: A2 - Guideline
pralsetinib
Sensitive
:
A2
pralsetinib
Sensitive: A2 - Guideline
pralsetinib
Sensitive
:
A2
RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
alectinib
Sensitive: C2 – Inclusion Criteria
alectinib
Sensitive
:
C2
alectinib
Sensitive: C2 – Inclusion Criteria
alectinib
Sensitive
:
C2
RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
sunitinib
Sensitive: C2 – Inclusion Criteria
sunitinib
Sensitive
:
C2
sunitinib
Sensitive: C2 – Inclusion Criteria
sunitinib
Sensitive
:
C2
RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
vandetanib
Sensitive: C3 – Early Trials
vandetanib
Sensitive
:
C3
vandetanib
Sensitive: C3 – Early Trials
vandetanib
Sensitive
:
C3
RET rearrangement
Non Small Cell Lung Cancer
RET rearrangement
Non Small Cell Lung Cancer
selpercatinib + pralsetinib
Sensitive: C3 – Early Trials
selpercatinib + pralsetinib
Sensitive
:
C3
selpercatinib + pralsetinib
Sensitive: C3 – Early Trials
selpercatinib + pralsetinib
Sensitive
:
C3
RET rearrangement
Lung Adenocarcinoma
RET rearrangement
Lung Adenocarcinoma
cabozantinib tablet
Sensitive: C3 – Early Trials
cabozantinib tablet
Sensitive
:
C3
cabozantinib tablet
Sensitive: C3 – Early Trials
cabozantinib tablet
Sensitive
:
C3
RET rearrangement
Thyroid Gland Carcinoma
RET rearrangement
Thyroid Gland Carcinoma
selumetinib
Sensitive: D – Preclinical
selumetinib
Sensitive
:
D
selumetinib
Sensitive: D – Preclinical
selumetinib
Sensitive
:
D
RET rearrangement
Thyroid Gland Papillary Carcinoma
RET rearrangement
Thyroid Gland Papillary Carcinoma
MK-2206
Sensitive: D – Preclinical
MK-2206
Sensitive
:
D
MK-2206
Sensitive: D – Preclinical
MK-2206
Sensitive
:
D
RET rearrangement
Thyroid Gland Carcinoma
RET rearrangement
Thyroid Gland Carcinoma
AZD1480
Sensitive: D – Preclinical
AZD1480
Sensitive
:
D
AZD1480
Sensitive: D – Preclinical
AZD1480
Sensitive
:
D
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