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BIOMARKER:
RET-PTC1 rearrangement
i
Other names:
RET, Ret Proto-Oncogene, Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret, Cadherin-Related Family Member 16, Rearranged During Transfection, RET Receptor Tyrosine Kinase, Cadherin Family Member 12, Proto-Oncogene C-Ret, CDHF12, CDHR16, PTC, Ret Proto-Oncogene (Multiple Endocrine Neoplasia And Medullary Thyroid Carcinoma 1, Hirschsprung Disease), Multiple Endocrine Neoplasia And Medullary Thyroid Carcinoma 1, Hirschsprung Disease 1, RET-ELE1, HSCR1, MEN2A, MEN2B, RET51, MTC1, PTC1, Patched Ho
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Entrez ID:
5979
;
5727
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
KIF5B-RET fusion + RET G810C (3)
EGFR mutation + RET fusion (2)
KIF5B-RET fusion + RET G810S (2)
CCDC6-RET fusion + EGFR mutation (1)
CCDC6‐RET fusion + TERT promotor mutation (1)
GPRC6A-RET fusion + EGFR mutation (1)
KIF5B-RET fusion + EGFR exon 19 deletion (1)
KIF5B-RET fusion + MET amplification (1)
KIF5B-RET fusion + RET E732K (1)
KIF5B-RET fusion + RET L730I (1)
KIF5B-RET fusion + RET L730V (1)
KIF5B-RET fusion + RET M918T (1)
KIF5B-RET fusion + RET V804E (1)
KIF5B-RET fusion + RET V804M (1)
KIF5B-RET fusion + TP53 H193R + MYC amplification (1)
MET amplification + RET fusion (1)
PD-L1 overexpression + RET-CCDC6 fusion (1)
PD-L1 overexpression + RET-KIF5B fusion (1)
PD-L1 overexpression + RET-KIF5B fusion + TP53 mutation + AR mutation + RET rearrangement (1)
RET G810C + CCDC6-RET fusion (1)
RET amplification + TMB-H + PD-L1 expression (1)
RET positive + KRAS G12V (1)
RET positive + SMARCA4 mutation (1)
RET-MIR4299-MIR8070 fusion + RET amplification (1)
SHTN1-RET fusion + EGFR mutation (1)
SPECC1-RET fusion + EGFR mutation (1)
TLN1-RET fusion + EGFR mutation (1)
TRIM24-RET fusion + EGFR mutation (1)
TRIM33-RET fusion + EGFR mutation (1)
PTCH1 1504-1G>T + TMB-H (1)
KIF5B-RET fusion + RET G810C (3)
EGFR mutation + RET fusion (2)
KIF5B-RET fusion + RET G810S (2)
CCDC6-RET fusion + EGFR mutation (1)
CCDC6‐RET fusion + TERT promotor mutation (1)
GPRC6A-RET fusion + EGFR mutation (1)
KIF5B-RET fusion + EGFR exon 19 deletion (1)
KIF5B-RET fusion + MET amplification (1)
KIF5B-RET fusion + RET E732K (1)
KIF5B-RET fusion + RET L730I (1)
KIF5B-RET fusion + RET L730V (1)
KIF5B-RET fusion + RET M918T (1)
KIF5B-RET fusion + RET V804E (1)
KIF5B-RET fusion + RET V804M (1)
KIF5B-RET fusion + TP53 H193R + MYC amplification (1)
MET amplification + RET fusion (1)
PD-L1 overexpression + RET-CCDC6 fusion (1)
PD-L1 overexpression + RET-KIF5B fusion (1)
PD-L1 overexpression + RET-KIF5B fusion + TP53 mutation + AR mutation + RET rearrangement (1)
RET G810C + CCDC6-RET fusion (1)
RET amplification + TMB-H + PD-L1 expression (1)
RET positive + KRAS G12V (1)
RET positive + SMARCA4 mutation (1)
RET-MIR4299-MIR8070 fusion + RET amplification (1)
SHTN1-RET fusion + EGFR mutation (1)
SPECC1-RET fusion + EGFR mutation (1)
TLN1-RET fusion + EGFR mutation (1)
TRIM24-RET fusion + EGFR mutation (1)
TRIM33-RET fusion + EGFR mutation (1)
PTCH1 1504-1G>T + TMB-H (1)
›
Associations
News
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VERI cancer hierarchy
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RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
MK-2206
Sensitive: D – Preclinical
MK-2206
Sensitive
:
D
MK-2206
Sensitive: D – Preclinical
MK-2206
Sensitive
:
D
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
dasatinib + CI-1040
Sensitive: D – Preclinical
dasatinib + CI-1040
Sensitive
:
D
dasatinib + CI-1040
Sensitive: D – Preclinical
dasatinib + CI-1040
Sensitive
:
D
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
dasatinib
Sensitive: D – Preclinical
dasatinib
Sensitive
:
D
dasatinib
Sensitive: D – Preclinical
dasatinib
Sensitive
:
D
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
cabozantinib capsule
Sensitive: D – Preclinical
cabozantinib capsule
Sensitive
:
D
cabozantinib capsule
Sensitive: D – Preclinical
cabozantinib capsule
Sensitive
:
D
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
CI-1040 + SU6656
Sensitive: D – Preclinical
CI-1040 + SU6656
Sensitive
:
D
CI-1040 + SU6656
Sensitive: D – Preclinical
CI-1040 + SU6656
Sensitive
:
D
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
CI-1040 + PP2
Sensitive: D – Preclinical
CI-1040 + PP2
Sensitive
:
D
CI-1040 + PP2
Sensitive: D – Preclinical
CI-1040 + PP2
Sensitive
:
D
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
CI-1040
Sensitive: D – Preclinical
CI-1040
Sensitive
:
D
CI-1040
Sensitive: D – Preclinical
CI-1040
Sensitive
:
D
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
RET-PTC1 rearrangement
Thyroid Gland Papillary Carcinoma
AZD1480
Sensitive: D – Preclinical
AZD1480
Sensitive
:
D
AZD1480
Sensitive: D – Preclinical
AZD1480
Sensitive
:
D
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