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    Association details:
    Biomarker:RET-PTC1 rearrangement
    Cancer:Thyroid Gland Papillary Carcinoma
    Drug:dasatinib (c-KIT inhibitor, Bcr-abl tyrosine kinase inhibitor, Src kinase inhibitor, EphA2 receptor antagonist, PDGFR β antagonist)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    New
    Source:
    Head Neck
    Title:

    Src Inhibitors Suppress the Growth of Papillary Thyroid Carcinoma

    Excerpt:
    Using an orthotopic xenograft mouse model, a significant reduction in average tumor volume was observed in TPC-1 mice treated with dasatinib…
    DOI:
    10.1002/hed.23316