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BIOMARKER:

RB1 overexpression

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Entrez ID:

Related biomarkers:

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EGFR exon 19 deletion + TP53 mutation + RB1 mutation (2)

BRAF V600E + CDKN2A deletion + RB1 expression (1)

BRAF V600K + CDKN2A deletion + RB1 expression (1)

BRCA1 mutation + RB1 deletion (1)

BRCA2 mutation + RB1 deletion (1)

EGFR C797S + KRAS amplification + RB1 deletion (1)

EGFR L858R + KRAS amplification + RB1 deletion (1)

EGFR T790M + KRAS amplification + RB1 deletion (1)

HR positive + RB1 mutation (1)

MET amplification + RB1 wild-type (1)

RB1 mutation + HR positive (1)

RB1 mutation + PD-L1 expression (1)

TMB-H + RB1 mutation + PD-L1 underexpression (1)

TMB-H + RB1 L518fs*6 + ERCC4 R799W + TP53 C124* (1)

TMB-L + RB1 mutation (1)

TP53 deletion + RB1 deletion + CTSK expression (1)

EGFR exon 19 deletion + TP53 mutation + RB1 mutation (2)

BRAF V600E + CDKN2A deletion + RB1 expression (1)

BRAF V600K + CDKN2A deletion + RB1 expression (1)

BRCA1 mutation + RB1 deletion (1)

BRCA2 mutation + RB1 deletion (1)

EGFR C797S + KRAS amplification + RB1 deletion (1)

EGFR L858R + KRAS amplification + RB1 deletion (1)

EGFR T790M + KRAS amplification + RB1 deletion (1)

HR positive + RB1 mutation (1)

MET amplification + RB1 wild-type (1)

RB1 mutation + HR positive (1)

RB1 mutation + PD-L1 expression (1)

TMB-H + RB1 mutation + PD-L1 underexpression (1)

TMB-H + RB1 L518fs*6 + ERCC4 R799W + TP53 C124* (1)

TMB-L + RB1 mutation (1)

TP53 deletion + RB1 deletion + CTSK expression (1)

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RB1 overexpression	Breast Cancer	RB1 overexpression	Breast Cancer	palbociclib Resistant: B - Late Trials palbociclib Resistant : B	palbociclib Resistant: B - Late Trials palbociclib Resistant : B
RB1 overexpression	Ovarian Cancer	RB1 overexpression	Ovarian Cancer	palbociclib Sensitive: D – Preclinical palbociclib Sensitive : D	palbociclib Sensitive: D – Preclinical palbociclib Sensitive : D